GONZÁLEZ SEVINE, Asier

Academic training

PhD in Biotechnology, UNIVERSITAT AUTÒNOMA DE BARCELONA
Graduate in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA

Professional experience

Licentiate degree in Biochemistry (2003) and PhD in Biotechnology (2010) from the Universitat Autònoma de Barcelona. My PhD research in the laboratory of Prof. Joaquin Ariño focused i) on the functional characterization of type 2C protein phosphatase family members in the yeast Saccharomyces cerevisiae, my main working model ever since and ii) on elucidating the role of the Ppz1 phosphatase regulatory subunits Hal3, Vhs3 and Cab3 on coenzyme A biosynthesis. In my first postdoctoral stage (2012-2018) at the laboratory of Prof. Michael N. Hall (Biozentrum of the University of Basel, Switzerland) I focused on the characterization of nutrient signaling pathways regulating TOR kinase, the central controller of growth. Leveraging my expertise on TOR signaling, I ventured into entrepreneurship together with Dr. Stefan Imseng at a technology venture (Aukera) from 2018 to 2021 having Prof. Michael N. Hall and Prof. Timm Maier as advisors. Our research to develop novel and selective mTORC1 inhibitors led to the foundation of a start-up. In 2022, I joined the laboratory of Prof. Mihaela Zavolan (Biozentrum of the University of Basel, Switzerland) as a research associate to study fundamental mechanisms of translation control in yeast and their deregulation in cancer. In March 2024 I joined the Department of Biochemistry and Molecular Biology of the Universitat Autònoma de Barcelona as an Assistant professor (Profesor lector). My aim is to establish my own research group on deciphering mechanisms of translational control during stress and disease.