Directory
MIRALPEIX MONCLÚS, Cristina
Department of Basic Areas
Regulació del metabolisme lipídic en l'obesitat i la diabetis (METALIP)
MIRALPEIX MONCLÚS, Cristina
CV
Teacher profile
Basic Areas, DEPARTMENT OF BASIC SCIENCIES. Universitat Internacional de Catalunya
Education
PhD in Health Sciences, INTERNATIONAL UNIVERSITY OF CATALONIA
Master's Degree in Neurosciences, UNIVERSITAT AUTÒNOMA DE BARCELONA
Graduated in Biochemistry, UNIVERSITAT DE BARCELONA
Master's Degree in Neurosciences, UNIVERSITAT AUTÒNOMA DE BARCELONA
Graduated in Biochemistry, UNIVERSITAT DE BARCELONA
Professional experience
Postdoctoral Researcher INSERM, 2020 – actualidad, Bordeaux, Nouvelle-Aquitaine, France
PhD Student UIC Barcelona, 2015 - ene.
Researcher, UIC Barcelona, 2014 – 2015, Basic Science Department, Master's Thesis in "Study of the interaction between CPT1C and plamitoyl-CoA and its inhibition by malonyl-CoA."
Researcher, University of Zurich, 2014 – 2014 University Clinic of Child and Adolescent Psychiatry Bachelor reasearch project in "Oxytocin and Arginine Vasopressin effect in neurons viability and differentiation studied in rat Raphe nucleus RN46A cells."
PhD Student UIC Barcelona, 2015 - ene.
Researcher, UIC Barcelona, 2014 – 2015, Basic Science Department, Master's Thesis in "Study of the interaction between CPT1C and plamitoyl-CoA and its inhibition by malonyl-CoA."
Researcher, University of Zurich, 2014 – 2014 University Clinic of Child and Adolescent Psychiatry Bachelor reasearch project in "Oxytocin and Arginine Vasopressin effect in neurons viability and differentiation studied in rat Raphe nucleus RN46A cells."
Publications
Articles
- Fosch, A.; Rodriguez, M.; Miralpeix, C.; Zagmutt, S.; Larrañaga, M.; Reguera, AC.; Garcia, J.; Herrero, L.; Serra, D.; Casals, N; Rodriguez-Rodriguez, R., (2023), "Central Regulation of Brown Fat Thermogenesis in Response to Saturated or Unsaturated Long-Chain Fatty Acids", International Journal of Molecular Sciences, vol. 24, No. 2, ISSN: 1422-0067.
- Lillo, A.; Lillo, J.; Raïch, I.; Miralpeix, C.; Dosrius, F.; Franco, R.; Navarro, G., (2021), "Ghrelin and Cannabinoid Functional Interactions Mediated by Ghrelin/CB1 Receptor Heteromers That Are Upregulated in the Striatum From Offspring of Mice Under a High-Fat Diet", Frontiers in Cellular Neuroscience, vol. 15, ISSN: 1662-5102.
- Miralpeix, C.; Reguera, AC.; Fosch, A.; Zagmutt, S.; Casals, N; Cota, D.; Rodriguez-Rodriguez, R., (2021), "Hypothalamic endocannabinoids in obesity: an old story with new challenges", Cellular and molecular life sciences, vol. 78, No. 23, pp. 7469-7490, ISSN: 1420-682X.
- Lillo, J.; Lillo, A.; Zafra, D.A.; Miralpeix, C.; Rivas-Santisteban, R.; Casals, N; Navarro, G.; Franco, R., (2021), "Identification of the ghrelin and cannabinoid cb2 receptor heteromer functionality and marked upregulation in striatal neurons from offspring of mice under a high-fat diet", International Journal of Molecular Sciences, vol. 22, No. 16, ISSN: 1422-0067.
- Rodriguez-Rodriguez, R.; Miralpeix, C., (2021), "Hypothalamic Regulation of Obesity", International Journal of Molecular Sciences, vol. 22, No. 24, ISSN: 1422-0067.
- Miralpeix, C.; Reguera, AC.; Fosch, A.; Casas, M.; Lillo, J.; Navarro, G.; Franco, R.; Casas, J.; Alexander, S.P.H.; Casals, N; Rodriguez-Rodriguez, R., (2021), "Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status", British journal of pharmacology, vol. 178, No. 7, pp. 1507-1523, ISSN: 0007-1188.
- Miralpeix, C.; Fosch, A.; Casas, J.; Baena, M.; Herrero, L.; Serra, D.; Rodriguez-Rodriguez, R.; Casals, N, (2019), "Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice", Journal of lipid research, vol. 60, No. 7, pp. 1260-1269, ISSN: 0022-2275.
- Rodriguez-Rodriguez, R.; Miralpeix, C.; Fosch, A.; Pozo Ariza, M; Calderón Domínguez, M.; Perpinyà, X.; Vellvehi, M.; López, M.; Herrero, L.; Serra, D.; Casals, N, (2019), "CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity", Molecular Metabolism, vol. 19, pp. 75-85, ISSN: 2212-8778.
Projects and research
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Carnitine palmitoyltransferase 1-mediated strategies to activate brown fat and reduce food intake to fight against obesity01/03/2017 - 01/03/2020IP: Casals, N; Serra, D.
Fundació la Marató de TV3
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Regulation of Lipid Metabolism in Obesity and Diabetes (METALIP)01/01/2017 - 31/12/2019IP: Casals, N
Agencia de Gestió d'ajudas Universitaries Investigació AGAUR
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Papel de la carnitina pamitoil transferasa 1C como sensor hipotalámico de aciles-CoA y regulador del metabolismo periférico de los lípidos (SAF2014-52223-C2-2-R)01/01/2015 - 31/12/2017IP: Casals, N
Ministerio de Ciencia e Innovación (MICINN)
Activities
- Reunión Anual de la Sociedad Española de Investigación sobre Cannabinoides Presentació de poster "CPT1C AS THE FIRST NEGATIVE REGULATOR OF THE ENDOCANNABINOIDS α/β-HYDROLASE CONTAINING 6 (ABHD6)", 2019.
- Copenhagen Bioscience Conference- Metabolism in action Presentació de poster "Deciphering the cross-talk relationship between brown fat thermogenesis and hypothalamic endocannabinoid dynamics during obesity development", 2019.
- Gordon Research Conference on Cannabinoid Function in the CNS Presentació de comunicació "CPT1C: a novel regulator of ABHD6 activity", 2019.
- Gordon Research Conference on Cannabinoid Function in the CNS Presentació de poster "The dynamic of endocannabinoids in the hypothalamus during obesity development in male and female mice and its cross-talk to Brown fat thermogenesis", 2019.
- MetNet Annual Meeting: Targeting Metabolism to Develop New Therapies Presentació de comunicació "Carnitine palmitoyltransferase 1C as the first negative regulator of the endocannabinoids hydrolase ABHD6", 2019.
- EMBO Workshop- Organ crosstalk in energy balance and metabolic disease Presentació de poster "The dynamic of endocannabinoid levels in the hypothalamus negatively correlates with obesity development in male and female mice", 2019.
- Congreso de la Sociedad Española de Endocannabinoides Presentació de poster "Analysis of hypothalamic endocannabinoids fluctuations in response to high fat diet in male and female mice", 2017.
- Congreso de la Sociedad Española de Endocannabinoides Presentació de comunicació "ABHD6 and CPT1C interaction as a novel mechanism to regulate thermogenesis", 2017.
- EMBO Workshop Presentació de poster "Brain specific carnitine palmitoyltransferase 1C (CPT1C) is involved in the hypothalamic regulation of brown fat thermogenesis by endocannabinoids-dependent mechanisms", 2017.
- Copenhagen Bioscience Conference Presentació de poster "Brain specific CPT1C is involved in the hypothalamic regulation of brown fat thermogenesis by endocannabinoids-dependent mechanisms", 2017.