Directory
BAENA MUÑOZ, Miguel
Ext. 5224
Department of Basic Areas
From cell metabolism to metabolic diseases (METADIS)
BAENA MUÑOZ, Miguel
CV
Teacher profile
Professor Contractat Doctor
Basic Areas, DEPARTMENT OF BASIC SCIENCIES. Universitat Internacional de Catalunya
Academic curriculum
- Programa de Doctorado en Biomedicina Universitat de Barcelona
- Máster en Biomedicina Universitat de Barcelona
- Licenciatura en Biología Universitat de Barcelona
Publications
Articles
- Roglans, N.; Baena, M.; Sangüesa, G.; Velázquez, A.; Grinan-Ferre, C.; Pallas, M.; Sánchez, RM; Alegret, M.; Laguna, J., (2021), "Chronic liquid fructose supplementation does not cause liver tumorigenesis but elicits clear sex differences in the metabolic response in Sprague-Dawley rats", Food & Nutrition Research, vol. 65, ISSN: 1654-6628.
- Palomo-Guerrero, M.; Fadó, R.; Casas, M.; Pérez-Montero, M.; Baena, M.; Helmer, PO.; Domínguez, JL.; Roig, A.; Serra, D.; Hayen, H.; Stenmark, H.; Raiborg, C.; Casals, N, (2019), "Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth", eLife, vol. 8, ISSN: 2050-084X.
- Miralpeix, C.; Fosch, A.; Casas, J.; Baena, M.; Herrero, L.; Serra, D.; Rodriguez-Rodriguez, R.; Casals, N, (2019), "Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice", Journal of lipid research, vol. 60, No. 7, pp. 1260-1269, ISSN: 0022-2275.
- Sanguesa, G.; Montañés, J.; Baena, M.; Sánchez, R.; Roglans, N.; Alegret, M.; Laguna, J., (2019), "Chronic fructose intake does not induce liver steatosis and inflammation in female Sprague-Dawley rats, but causes hypertriglyceridemia related to decreased VLDL receptor expression", European journal of nutrition, vol. 58, No. 3, pp. 1283-1297, ISSN: 1436-6207.
- Sanguesa, G.; Roglans, N.; Baena, M.; Velázquez, A.; Laguna, J.; Alegret, M., (2019), "mTOR is a key protein involved in the metabolic effects of simple sugars", International Journal of Molecular Sciences, vol. 20, No. 5, ISSN: 1422-0067.
- Sangüesa, G.; Roglans, N.; Montañés, J.; Baena, M.; Velázquez, A.; Sánchez, RM.; Alegret, M.; Laguna, J., (2018), "Chronic liquid fructose, but not glucose, supplementation selectively induces visceral adipose tissue leptin resistance and hypertrophy in female sprague-dawley rats", Molecular nutrition and food research, vol. 62, No. 22, ISSN: 1613-4125.
- Sangüesa, G.; Baena, M.; Hutter, N.; Montañés, J.; Sánchez, R.; Roglans, N.; Laguna, J.; Alegret, M., (2017), "The addition of liquid fructose to a western-type diet in LDL-R-/- mice induces liver inflammation and fibrogenesis markers without disrupting insulin receptor signalling after an insulin challenge", Nutrients, vol. 9, No. 3, ISSN: 2072-6643.
- Baena, M.; Sangüesa, G.; Hutter, N.; Beltrán, J.; Sánchez, RM; Roglans, N.; Alegret, M.; Laguna, J., (2017), "Liquid fructose in western diet-fed mice impairs liver insulin signaling and causes cholesterol and triglyceride loading without changing calorie intake and body weight", Journal of nutritional biochemistry, vol. 40, pp. 105-115, ISSN: 0955-2863.
- Baena, M.; Sangüesa, G.; Dávalos, A.; Latasa, M.; Salá-Vilá, A.; Sánchez, R.; Roglans, N.; Laguna, J.; Alegret, M., (2016), "Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues", Scientific Reports, vol. 6, No. 26149, ISSN: 2045-2322.
- Hutter, N.; Baena, M.; Sangüesa, G.; Dávalos, A.; Latasa, M.; Escolá-Gil, J.; Sánchez, RM; Roglans, N.; Alegret, M.; Laguna, J., (2015), "Liquid fructose supplementation in LDLR−/− mice fed a western-type diet enhances lipid burden and atherosclerosis despite identical calorie consumption", International journal of cardiology, vol. 6, pp. 12-21, ISSN: 0167-5273.
- Pereira, L.; Medina, R.; Baena, M.; Planas, AM; Pozas, E., (2015), "IFN gamma regulates proliferation and neuronal differentiation by STAT1 in adult SVZ niche", Frontiers in Cellular Neuroscience, vol. 9, No. 270, ISSN: 1662-5102.
- Baena, M.; Sangüesa, G.; Hutter, N.; Sánchez, RM; Roglans, N.; Laguna, J.; Alegret, M., (2015), "Fructose supplementation impairs rat liver autophagy through mTORC activation without inducing endoplasmic reticulum stress", Biochimica et biophysica acta. Molecular and cell biology of lipids, vol. 1851, No. 2, pp. 107-116, ISSN: 1388-1981.
- Rebollo, A.; Roglans, N.; Baena, M.; Sánchez, RM; Merlos, M.; Alegret, M.; Laguna, J., (2014), "Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells", Biochimica et biophysica acta. Molecular and cell biology of lipids, vol. 1841, No. 4, pp. 514-524, ISSN: 1388-1981.
- Rebollo, A.; Roglans, N.; Baena, M.; Padrosa, A.; Sánchez, RM; Merlos, M.; Alegret, M.; Laguna, J., (2014), "Liquid fructose down-regulates liver insulin receptor substrate 2 and gluconeogenic enzymes by modifying nutrient sensing factors in rats", Journal of nutritional biochemistry, vol. 25, No. 2, pp. 250-258, ISSN: 0955-2863.
- Vilà, L.; Roglans, N.; Baena, M.; Barroso, E.; Alegret, M.; Merlos, M.; Laguna, J., (2012), "Metabolic alterations and increased liver mTOR expression precede the development of autoimmune disease in a murine model of lupus erythematosus", PLoS One, vol. 7, No. 12, ISSN: 1932-6203.
- Solé, M.; Baena, M.; Arnau, S.; Carrasson, M.; Maynou, F.; Cartes, J., (2010), "Muscular cholinesterase activities and lipid peroxidation levels as biomarkers in several Mediterranean marine fish species and their relationship with ecological variables", Environment international, vol. 36, No. 2, pp. 202-211, ISSN: 0160-4120.
- Solé, M.; Antó, M.; Baena, M.; Carrasson, M.; Cartes, J.; Maynou, F., (2010), "Hepatic biomarkers of xenobiotic metabolism in eighteen marine fish from NW Mediterranean shelf and slope waters in relation to some of their biological and ecological variables", Marine environmental research, vol. 70, No. 2, pp. 181-188, ISSN: 0141-1136.
Book chapters
- Baena, M., (2014), "Fructose effects on human health: Molecular insights from experimental models", Recent Advances in Pharmaceutical Sciences IV, pp. 1-19. ISBN: 978-81-308 0554-2.
- Baena, M., (2012), "Fructose induces synthesis and reduces oxidation of liver fatty acids through CHREBP activation", Actualidad en Farmacología y Terapeútica, pp. 289-291. ISBN: 1698-4277.
Projects and research
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Cpt1c en el hipotálamo ventromedial como nueva diana terapéutica en la regulación del balance energético: mecanismos moleculares implicados01/01/2018 - 31/12/2020IP: Casals, N; Rodriguez-Rodriguez, R.
Ministerio de Economía, Industria y Competitividad
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Carnitine palmitoyltransferase 1- mediated strategies to activate brown fat and reduce food intake to fight against obesity01/03/2017 - 31/03/2020IP: Casals, N.
Fundació la Marató de TV3
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Carnitine palmitoyltransferase 1-mediated strategies to activate brown fat and reduce food intake to fight against obesity01/03/2017 - 01/03/2020IP: Casals, N; Serra, D.
Fundació la Marató de TV3
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Regulation of Lipid Metabolism in Obesity and Diabetes (METALIP)01/01/2017 - 31/12/2019IP: Casals, N
Agencia de Gestió d'ajudas Universitaries Investigació AGAUR
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Receptors nuclears, Metabolisme energétic i Terapia de les malalties del metabolisme01/01/2015 - 31/12/2017IP: Laguna, J.
Generalitat de Catalunya
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El consumo continuado de fructosa en forma líquida como promotor de enfermedades crónicas relacionadas con alteraciones en el equilibrio energético01/01/2014 - 31/12/2016IP: Laguna, J.
Ministerio de Economía, Industria y Competitividad
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Implicación de SIRT1 y la adiponectina en las alteraciones metabólicas inducidas por la ingesta de fructosa en forma líquida01/09/2011 - 30/07/2015IP: Laguna, J.
Ministerio de Economía, Industria y Competitividad
Activities
- EMBO virtual Workshop Presentació de poster "Expression, purification, and crystallization of Carnitine Palmitoyltransferase 1 Proteins (Brain And Liver Isoforms)", 2021.
- Joint Meeting of the French-Portuguese-Spanish Biochemical and Molecular Biology Societies Presentació de poster "Carnitine palmitoyltransferase 1C (CPT1C): How to measure its activity", 2017.
- European Atherosclerosis Society Presentació de poster "Liquid fructose in western diet-fed mice impairs liver insulin signaling and causes cholesterol and triglyceride loading without changing calorie intake and body weight", 2016.
- 84th International Congress of European Atherosclerosis Society Presentació de poster "High fructose consumption imparis aortic function and metabolic parameters compared to glucose in female rats", 2016.
- Dietary sugars, obesity and metabolic disease risk Presentació de poster "Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues", 2015.
- Congreso Nacional de la Sociedad Española de Arteriosclerosis (SEA) Presentació de comunicació "La suplementación con fructosa en condiciones isocalóricas con glucosa inhibe la vía de señalización de la insulina en sus órganos diana", 2015.
- Congreso de la Sociedad Española de Aterosclerosis Presentació de poster "La administración de fructosa, sola o combinada con dieta western, induce resistencia hepática a la leptina en el modelo de ratón C57BL/6N", 2014.
- XXVII Congreso Nacional de la Sociedad Española de Arterioesclerosis (SEA) Presentació de poster "La suplementación semicrónica de fructosa en rata reduce la autofagia hepática a través de la vía mTOR-Ulk1", 2014.
- Congreso de la Sociedad Española de Aterosclerosis Presentació de poster "La suplementación con fructosa líquida en el modelo de ratón Knock-Out para el receptor de las LDL induce lesión arterioesclerótica independientemente del consumo energético", 2014.
- Congreso de la Sociedad Española de Aterosclerosis Presentació de poster "La suplementación semicrónica de fructosa en rata induce hígado graso y resistencia a la insulina en ausencia de un estado proinflamatorio", 2014.