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FERNÁNDEZ LOBATO, Mercedes

FERNÁNDEZ LOBATO, Mercedes

Professor Col.laborador
DEPARTMENT OF BASIC SCIENCIES
Department of Basic Areas

Contact

mfernandezlo@uic.es
ORCID
  • Academic training
  • Professional experience
  • Publications
    • Articles
  • Subjects taught
Doctor Biology, University of Barcelona
Biology degree, University of Barcelona
Senior Group Leader at the IDIBAPS Biomedical Research Institute, University of Barcelona Medical School.

Publicacions
Pathological angiogenesis: New culprit behind chronic liver disease Ramirez M, Fernandez M
Corresponding author: Mercedes Fernandez OBM Hepatology and Gastroenterology 2019, Special Issue: “Exploring Novel Treatment Options for Liver Fibrosis: Can Anti-Angiogenics Succeed?”. Ed. M. Bartneck. Lidsen Publishing (doi: 10.21926)(in press) Invited Review

Pericytes in the gut Ramirez M, Pell N, Mejias M, Fernandez M Corresponding author: Mercedes Fernandez
Advances in Experimental Medicine and Biology 2019; 1122:73-100, “Pericyte Biology in Different Organs”, Ed. A. Birbrair. Springer Nature, Switzerland AG Invited Review

Placental growth factor: New treatment target bringing hope in hepatopulmonary syndrome Fernandez M Corresponding author: Mercedes Fernandez Hepatology (2018) 68:404-407 Invited Editorial

Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress
Maillo C, Martin J, Sebastian D, Hernandez-Alvarez M, Garcia-Rocha M, Reina O, Zorzano A, Fernandez M, Mendez R Co-corresponding authors: Raul Mendez and Mercedes Fernandez Nature Cell Biology (2017) 19:94-105 Comment on this paper: Moore PC & Oakes SA. CPEB4 links the clock and the UPR to protect the liver. Nature Cell Biology (2017);19:79-81. This paper received the Award to the Best Scientific Publication (Year 2018) from the Spanish Association Against Cancer (AECC)
  • Molecular Psychiatry, CPEB and translational control by cytoplasmic polyadenylation: Impact on synaptic plasticity, learning, and memory
    Name: Huang, Y.; Mendez, R.; Fernández, M.; Richter, J. Role: Autor Publishing date: 2023
    Start page: 2728 End page: 2736 Vol.: 28
    DOI: https://dx.doi.org/10.1038/s41380-023-02088-x ISSN or title: 1476-5578
  • Hepatology, Ductular reaction promotes intrahepatic angiogenesis through Slit2–Roundabout 1 signaling
    Name: Coll, M.; Ariño, S.; Martínez, C.; Garcia, E.; Gallego, J.; Moles, A.; Aguilar, B.; Blaya, D.; Vallverdú, J.; Rubio‐, T.; Lozano, J.; Pose, E.; Graupera, I.; Fernández, A.; Pol, A.; Bataller, R.; Geng, J.; Ginès, P.; Fernández, M.; Sancho, P. Role: Autor Publishing date: 2022
    Start page: 353 End page: 368 Vol.: 75 No.: 2
    DOI: https://dx.doi.org/10.1002/hep.32140 ISSN or title: 0270-9139
  • Iscience, Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development
    Name: Sibilio, A.; Suñer, C.; Fernández, M.; Martín, J.; Berenguer, A.; Calon, A.; Chanes, V.; Millanes, A.; Fernández, G.; Batlle, E.; Fernández, M.; Méndez, R. Role: Autor Publishing date: 2022
    Vol.: 25 No.: 2
    DOI: https://dx.doi.org/10.1016/j.isci.2022.103790 ISSN or title: 2589-0042
  • Cell Reports, Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes
    Name: Riechert, E.; Kmietczyk, V.; Stein, F.; Schwarzl, T.; Sekaran, T.; Jürgensen, L.; Kamuf, V.; Varma, E.; Hofmann, C.; Rettel, M.; Gür, K.; Ölschläger, J.; Kühl, F.; Martin, J.; Ramirez, M.; Fernández, M.; Doroudgar, S.; Méndez, R.; Katus, H.; Hentze, M.W.; Völkers, M. Role: Autor Publishing date: 2021
    Vol.: 35 No.: 6
    DOI: https://dx.doi.org/10.1016/j.celrep.2021.109100 ISSN or title: 2211-1247
  • Frontiers in Physiology, Translational control in liver disease
    Name: Balvey, A.; Fernández, M. Role: Autor Publishing date: 2021
    Vol.: 12
    DOI: https://dx.doi.org/10.3389/fphys.2021.795298 ISSN or title: 1664-042X
  • Molecular Metabolism, Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis
    Name: Pell, N.; Garcia, E.; Gallego, J.; Naranjo, S.; Balvey, A.; Suñer, C.; Fernandez, M.; Chanes, V.; Carbo, J.; Ramirez, M.; Reina, O.; Thingholm, L.; Bang, C.; Rühlemann, M.; Franke, A.; Schierwagen, R.; Rheinwalt, K.; Trebicka, J.; Mendez, R.; Fernández, M. Role: Autor Publishing date: 2021
    Vol.: 54
    DOI: https://dx.doi.org/10.1016/j.molmet.2021.101388 ISSN or title: 2212-8778
  • Gastroenterology, CPEB4 increases expression of PFKFB3 to induce glycolysis and activate mouse and human hepatic stellate cells, promoting liver fibrosis
    Name: Mejias, M.; Gallego, J.; Naranjo, S.; Ramirez, M.; Pell, N.; Manzano, A.; Suñer, C.; Bartrons, R.; Mendez, R.; Fernández, M. Role: Autor Publishing date: 2020
    Start page: 273 End page: 288 Vol.: 159 No.: 1
    DOI: https://dx.doi.org/10.1053/j.gastro.2020.03.008 ISSN or title: 0016-5085
  • Frontiers in Immunology, Interplay between macrophages and angiogenesis: A double-edged sword in liver disease
    Name: Ramirez, M.; Fernández, M. Role: Autor Publishing date: 2019
    Vol.: 10
    DOI: https://dx.doi.org/10.3389/fimmu.2019.02882 ISSN or title: 1664-3224
  • NATURE CELL BIOLOGY, Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress
    Name: Maillo, C.; Martín, J.; Sebastián, D.; Hernández, M.; García, M.; Reina, O.; Zorzano, A.; Fernández, M.; Méndez, R. Role: Autor Publishing date: 2017
    Start page: 94 End page: 105 Vol.: 19
    DOI: https://dx.doi.org/10.1038/ncb3461 ISSN or title: 1476-4679
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Introduction to Biomedicine
  • Official Master
    University Master's Degree in Experimental Biomedical Research
    • - Cancer Research
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Introduction to Biomedicine
    • - Structure and Function: Gastrointestinal and Reproductive Systems
  • Official Master
    University Master's Degree in Experimental Biomedical Research
    • - Cancer Research
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Introduction to Biomedicine
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Introduction to Biomedicine
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems

Academic training

Doctor Biology, University of Barcelona
Biology degree, University of Barcelona

Professional experience

Senior Group Leader at the IDIBAPS Biomedical Research Institute, University of Barcelona Medical School.

Publicacions
Pathological angiogenesis: New culprit behind chronic liver disease Ramirez M, Fernandez M
Corresponding author: Mercedes Fernandez OBM Hepatology and Gastroenterology 2019, Special Issue: “Exploring Novel Treatment Options for Liver Fibrosis: Can Anti-Angiogenics Succeed?”. Ed. M. Bartneck. Lidsen Publishing (doi: 10.21926)(in press) Invited Review

Pericytes in the gut Ramirez M, Pell N, Mejias M, Fernandez M Corresponding author: Mercedes Fernandez
Advances in Experimental Medicine and Biology 2019; 1122:73-100, “Pericyte Biology in Different Organs”, Ed. A. Birbrair. Springer Nature, Switzerland AG Invited Review

Placental growth factor: New treatment target bringing hope in hepatopulmonary syndrome Fernandez M Corresponding author: Mercedes Fernandez Hepatology (2018) 68:404-407 Invited Editorial

Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress
Maillo C, Martin J, Sebastian D, Hernandez-Alvarez M, Garcia-Rocha M, Reina O, Zorzano A, Fernandez M, Mendez R Co-corresponding authors: Raul Mendez and Mercedes Fernandez Nature Cell Biology (2017) 19:94-105 Comment on this paper: Moore PC & Oakes SA. CPEB4 links the clock and the UPR to protect the liver. Nature Cell Biology (2017);19:79-81. This paper received the Award to the Best Scientific Publication (Year 2018) from the Spanish Association Against Cancer (AECC)

Publications

Articles

  • Molecular Psychiatry, CPEB and translational control by cytoplasmic polyadenylation: Impact on synaptic plasticity, learning, and memory
    Name: Huang, Y.; Mendez, R.; Fernández, M.; Richter, J. Role: Autor Publishing date: 2023
    Start page: 2728 End page: 2736 Vol.: 28
    DOI: https://dx.doi.org/10.1038/s41380-023-02088-x ISSN or title: 1476-5578
  • Hepatology, Ductular reaction promotes intrahepatic angiogenesis through Slit2–Roundabout 1 signaling
    Name: Coll, M.; Ariño, S.; Martínez, C.; Garcia, E.; Gallego, J.; Moles, A.; Aguilar, B.; Blaya, D.; Vallverdú, J.; Rubio‐, T.; Lozano, J.; Pose, E.; Graupera, I.; Fernández, A.; Pol, A.; Bataller, R.; Geng, J.; Ginès, P.; Fernández, M.; Sancho, P. Role: Autor Publishing date: 2022
    Start page: 353 End page: 368 Vol.: 75 No.: 2
    DOI: https://dx.doi.org/10.1002/hep.32140 ISSN or title: 0270-9139
  • Iscience, Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development
    Name: Sibilio, A.; Suñer, C.; Fernández, M.; Martín, J.; Berenguer, A.; Calon, A.; Chanes, V.; Millanes, A.; Fernández, G.; Batlle, E.; Fernández, M.; Méndez, R. Role: Autor Publishing date: 2022
    Vol.: 25 No.: 2
    DOI: https://dx.doi.org/10.1016/j.isci.2022.103790 ISSN or title: 2589-0042
  • Cell Reports, Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes
    Name: Riechert, E.; Kmietczyk, V.; Stein, F.; Schwarzl, T.; Sekaran, T.; Jürgensen, L.; Kamuf, V.; Varma, E.; Hofmann, C.; Rettel, M.; Gür, K.; Ölschläger, J.; Kühl, F.; Martin, J.; Ramirez, M.; Fernández, M.; Doroudgar, S.; Méndez, R.; Katus, H.; Hentze, M.W.; Völkers, M. Role: Autor Publishing date: 2021
    Vol.: 35 No.: 6
    DOI: https://dx.doi.org/10.1016/j.celrep.2021.109100 ISSN or title: 2211-1247
  • Frontiers in Physiology, Translational control in liver disease
    Name: Balvey, A.; Fernández, M. Role: Autor Publishing date: 2021
    Vol.: 12
    DOI: https://dx.doi.org/10.3389/fphys.2021.795298 ISSN or title: 1664-042X
  • Molecular Metabolism, Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis
    Name: Pell, N.; Garcia, E.; Gallego, J.; Naranjo, S.; Balvey, A.; Suñer, C.; Fernandez, M.; Chanes, V.; Carbo, J.; Ramirez, M.; Reina, O.; Thingholm, L.; Bang, C.; Rühlemann, M.; Franke, A.; Schierwagen, R.; Rheinwalt, K.; Trebicka, J.; Mendez, R.; Fernández, M. Role: Autor Publishing date: 2021
    Vol.: 54
    DOI: https://dx.doi.org/10.1016/j.molmet.2021.101388 ISSN or title: 2212-8778
  • Gastroenterology, CPEB4 increases expression of PFKFB3 to induce glycolysis and activate mouse and human hepatic stellate cells, promoting liver fibrosis
    Name: Mejias, M.; Gallego, J.; Naranjo, S.; Ramirez, M.; Pell, N.; Manzano, A.; Suñer, C.; Bartrons, R.; Mendez, R.; Fernández, M. Role: Autor Publishing date: 2020
    Start page: 273 End page: 288 Vol.: 159 No.: 1
    DOI: https://dx.doi.org/10.1053/j.gastro.2020.03.008 ISSN or title: 0016-5085
  • Frontiers in Immunology, Interplay between macrophages and angiogenesis: A double-edged sword in liver disease
    Name: Ramirez, M.; Fernández, M. Role: Autor Publishing date: 2019
    Vol.: 10
    DOI: https://dx.doi.org/10.3389/fimmu.2019.02882 ISSN or title: 1664-3224
  • NATURE CELL BIOLOGY, Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress
    Name: Maillo, C.; Martín, J.; Sebastián, D.; Hernández, M.; García, M.; Reina, O.; Zorzano, A.; Fernández, M.; Méndez, R. Role: Autor Publishing date: 2017
    Start page: 94 End page: 105 Vol.: 19
    DOI: https://dx.doi.org/10.1038/ncb3461 ISSN or title: 1476-4679
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Introduction to Biomedicine
  • Official Master
    University Master's Degree in Experimental Biomedical Research
    • - Cancer Research
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Introduction to Biomedicine
    • - Structure and Function: Gastrointestinal and Reproductive Systems
  • Official Master
    University Master's Degree in Experimental Biomedical Research
    • - Cancer Research
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Introduction to Biomedicine
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
    • - Introduction to Biomedicine
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Structure and Function: Gastrointestinal and Reproductive Systems