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CASALS FARRÉ, Núria

CASALS FARRÉ, Núria

Professor Catedràtic
DEPARTMENT OF BASIC SCIENCIES
Department of Basic Areas
From cell metabolism to metabolic diseases (METADIS)

Contact

Tel. +34 932 541 800
Ext. 5223, 4240
ncasals@uic.es
ORCID
  • Academic training
  • Projects
    • Competitive
    • Non-competitive
  • Publications
    • Articles
    • Books
  • Patents
  • Subjects taught
  • Doctora en Farmàcia
  • Universitat de Barcelona
  • Master en Economia de la Salut i Gestió Sanitària
  • Universitat de Barcelona/Universitat Pompeu Fabra
  • Farmàcia
  • Universitat de Barcelona
  • EXPLORANDO LA RELEVANCIA DE LA INTERACCION DE CPT1C CON OTRAS PROTEINAS EN LA REGULACION DE LA HOMEOSTASIS ENERGETICA Y EL DESARROLLO DE LA OBESIDAD
    PI: Casals, N; Rodriguez-Rodriguez, R. Start date: 01/09/2021 End date: 31/08/2024
    Financing entity: Ministerio de Ciencia e Innovación (MICINN)
  • Administracion de fármacos específicos de la CPT1 central: una novedosa estrategia basada en nanomedicina para combatir obesidad y cáncer
    PI: Rodriguez-Rodriguez, R. Start date: 01/01/2019 End date: 31/12/2021
    Financing entity: MINISTERIO DE CIENCIA E INNOVACION Financing entity code: PCI2018-092997
  • Cpt1c en el hipotálamo ventromedial como nueva diana terapéutica en la regulación del balance energético: mecanismos moleculares implicados
    PI: Casals, N; Rodriguez-Rodriguez, R. Start date: 01/01/2018 End date: 31/12/2020
    Financing entity: Ministerio de Economía, Industria y Competitividad Financing entity code: SAF2017-83813-C3-3-R
  • Carnitine palmitoyltransferase 1-mediated strategies to activate brown fat and reduce food intake to fight against obesity
    PI: Casals, N; Serra, D. Start date: 01/03/2017 End date: 01/03/2020
    Financing entity: Fundació la Marató de TV3 Financing entity code: 201627-31
  • Regulation of Lipid Metabolism in Obesity and Diabetes (METALIP)
    PI: Casals, N Start date: 01/01/2017 End date: 31/12/2019
    Financing entity: Agencia de Gestió d'ajudas Universitaries Investigació AGAUR Financing entity code: 2017 SGR 278
  • Papel de la carnitina pamitoil transferasa 1C como sensor hipotalámico de aciles-CoA y regulador del metabolismo periférico de los lípidos (SAF2014-52223-C2-2-R)
    PI: Casals, N Start date: 01/01/2015 End date: 31/12/2017
    Financing entity: Ministerio de Ciencia e Innovación (MICINN) Financing entity code: SAF2014-52223-C2-2-R
  • Searching new biomarkers and therapeutic targets related to cognitive deficits in early stages of Alzheimer's Disease: Role of AKAP79/150, CPT1C and SSAO/VAP-1 in Abmediated AMPAR dysfunction.
    PI: Casals, N; Rodríguez , J. Start date: 01/01/2015 End date: 31/12/2017
    Financing entity: Fundació la Marató de TV3
  • Participación de CPT1C en la síntesis de ceramidas y el control de la ingesta alimentaria
    PI: Casals, N Start date: 01/01/2012 End date: 31/12/2014
    Financing entity: Ministerio de Economía y Competitividad Financing entity code: SAF2011- 30520- c02-02
  • Homeostasi Energètica
    PI: Casals, N Start date: 26/11/2009 End date: 31/12/2014
    Financing entity: Generalitat de Catalunya Financing entity code: 2009 SRG 1376
  • Bases moleculars de acción de las carnitina aciltransferasas como reguladoras de la oxidación de las grasas y su papel en la obesidad, la resistencia a la insulina y el apetito
    PI: Hegardt , FG. Start date: 01/01/2008 End date: 31/12/2012
    Financing entity: Ministerio de Ciencia y Tecnología Financing entity code: SAF2007-61926
  • Càtedra cultura, ciència i religió
    PI: Corcó, Josep Start date: 01/09/2013 End date: 31/08/2016
    Financing entity: FUNDACIÓ BARCELONA I FAMÍLIA
  • Efecto del Nucleo CMP Forte en la regeneración neuronal del Sistema Nervioso Periférico
    PI: Casals, N Start date: 01/05/2011 End date: 01/05/2012
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Neuroprotección del núcleo CMP forte en células nerviosas
    PI: Casals, N Start date: 01/01/2006 End date: 31/12/2007
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Estudio del papel neuroprotector de la CDP-colina en la muerte neuronal inducida por el péptido beta-amiloide y el NO
    PI: Casals, N Start date: 01/01/2002 End date: 31/12/2003
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Estudio del papel de la CDP-colina en la reducción de la apopotosis neuronal inducida por excitotoxicidad
    PI: Casals, N Start date: 01/01/1999 End date: 31/12/2000
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Biology of Sex Differences, CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
    Name: Zagmutt, S.; Mera, P.; González, I.; Ibeas, K.; Romero, M.; Obri, A.; Martin, B.; Esteve, A.; Soler-Vázquez, M.C.; Bastias, M.; Cañes, L.; Augé, E.; Pelegri, C.; Vilaplana, J.; Ariza, X.; García, J.; Martinez, J.; Casals, N; López, M.; Palmiter, R.; Sanz, E.; Quintana, A.; Herrero, L.; Serra, D. Role: Autor Publishing date: 2023
    Vol.: 14 No.: 1
    DOI: https://dx.doi.org/10.1186/s13293-023-00498-8 ISSN or title: 2042-6410
  • Metabolic engineering, Implantation of CPT1AM-expressing adipocytes reduces obesity and glucose intolerance in mice
    Name: Soler-Vázquez, M.C.; Romero, M.; Todorcevic, M.; Delgado, K.; Calatayud, C.; Benitez, A.; La Chica, M.; Mera, P.; Zagmutt, S.; Bastías, M.; Ibeas, K.; Casals, N; Escolà, J.; Llorente-Cortés, V.; Consiglio, A.; Serra, D.; Herrero, L. Role: Autor Publishing date: 2023
    Start page: 256 End page: 272 Vol.: 77
    DOI: https://dx.doi.org/10.1016/j.ymben.2023.04.010 ISSN or title: 1096-7176
  • Journal of Physiology, CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non-associative learning
    Name: Iborra, G.; Djebari, S.; Sánchez, I.; Gratacòs, E.; Sánchez, N.; Radošević, M.; Casals, N; de Dios, J.; Soto, D.; Jiménez, L. Role: Autor Publishing date: 2023
    Start page: 3533 End page: 3556 Vol.: 601 No.: 16
    DOI: https://dx.doi.org/10.1113/JP284248 ISSN or title: 1469-7793
  • European journal of neuroscience, XIth Cajal Conference: New frontiers in neuron-glial plasticity in health and disease
    Name: Louail, A.; Bengoetxea, I.; Rojas, R.; Casals, N Role: Autor Publishing date: 2023
    Start page: 1447 End page: 1465 Vol.: 57 No.: 9
    DOI: https://dx.doi.org/10.1111/ejn.15960 ISSN or title: 0953-816X
  • Biomaterials science, Nanomedicine targeting brain lipid metabolism as a feasible approach for controlling the energy balance
    Name: Garcia, J.; Paraiso, W.; Zagmutt, S.; Fosch, A.; Reguera, AC.; Alzina, S.; Sánchez, L.; Fukushima, S.; Toh, K.; Casals, N; Serra, D.; Herrero, L.; Garcia, J.; Kataoka, K.; Ariza, X.; Quader, S.; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2023
    Start page: 2336 End page: 2347 Vol.: 11
    DOI: https://dx.doi.org/10.1039/d2bm01751b ISSN or title: 2047-4830
  • JOURNAL OF NEUROENDOCRINOLOGY, Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: A promising strategy to regulate energy balance
    Name: Rodriguez-Rodriguez, R.; Fosch, A.; Garcia, J.; Zagmutt, S.; Casals, N Role: Autor Publishing date: 2023
    Vol.: 35 No.: 9
    DOI: https://dx.doi.org/10.1111/jne.13234 ISSN or title: 1365-2826
  • Cell death and disease, To be or not to be a fat burner, that is the question for cpt1c in cancer cells
    Name: Fadó, R.; Zagmutt, S.; Herrero, L.; Muley, H.; Rodriguez-Rodriguez, R.; Bi, H.; Serra, D.; Casals, N Role: Autor Publishing date: 2023
    Vol.: 14 No.: 1
    DOI: https://dx.doi.org/10.1038/s41419-023-05599-1 ISSN or title: 2041-4889
  • International Journal of Molecular Sciences, Central Regulation of Brown Fat Thermogenesis in Response to Saturated or Unsaturated Long-Chain Fatty Acids
    Name: Fosch, A.; Rodriguez, M.; Miralpeix, C.; Zagmutt, S.; Larrañaga, M.; Reguera, AC.; Garcia, J.; Herrero, L.; Serra, D.; Casals, N; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2023
    Vol.: 24 No.: 2
    DOI: https://dx.doi.org/10.3390/ijms24021697 ISSN or title: 1422-0067
  • International Journal of Molecular Sciences, Cpt1c Downregulation Causes Plasma Membrane Remodelling and Anthracycline Resistance in Breast Cancer
    Name: Muley, H.; Valencia, K.; Casas, J.; Moreno, B.; Botella, L.; Lecanda, F.; Fadó, R.; Casals, N Role: Autor Publishing date: 2023
    Vol.: 24 No.: 2
    DOI: https://dx.doi.org/10.3390/ijms24020946 ISSN or title: 1422-0067
  • Nutrients, Feeding the Brain: Effect of Nutrients on Cognition, Synaptic Function, and AMPA Receptors
    Name: Fadó, R.; Molins, A.; Rojas, R.; Casals, N Role: Autor Publishing date: 2022
    Vol.: 14 No.: 19
    DOI: https://dx.doi.org/10.3390/nu14194137 ISSN or title: 2072-6643
  • Cellular and molecular life sciences, Hypothalamic endocannabinoids in obesity: an old story with new challenges
    Name: Miralpeix, C.; Reguera, AC.; Fosch, A.; Zagmutt, S.; Casals, N; Cota, D.; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2021
    Start page: 7469 End page: 7490 Vol.: 78 No.: 23
    DOI: https://dx.doi.org/10.1007/s00018-021-04002-6 ISSN or title: 1420-682X
  • Biomaterials science, Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells
    Name: Paraiso, W.; Garcia, J.; Ariza, J.; Zagmutt, S.; Fukushima, S.; Garcia, J.; Mochida, Y.; Serra, D.; Herrero, L.; Kinoh, H.; Casals, N; Kataoka, K.; Rodriguez-Rodriguez, R.; Quader, S. Role: Autor Publishing date: 2021
    Start page: 7076 End page: 7091 Vol.: 9 No.: 21
    DOI: https://dx.doi.org/10.1039/d1bm00689d ISSN or title: 2047-4830
  • International Journal of Molecular Sciences, Identification of the ghrelin and cannabinoid cb2 receptor heteromer functionality and marked upregulation in striatal neurons from offspring of mice under a high-fat diet
    Name: Lillo, J.; Lillo, A.; Zafra, D.A.; Miralpeix, C.; Rivas-Santisteban, R.; Casals, N; Navarro, G.; Franco, R. Role: Autor Publishing date: 2021
    Vol.: 22 No.: 16
    DOI: https://dx.doi.org/10.3390/ijms22168928 ISSN or title: 1422-0067
  • International Journal of Molecular Sciences, New insights of sf1 neurons in hypothalamic regulation of obesity and diabetes
    Name: Fosch, A.; Zagmutt, S.; Casals, N; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2021
    Vol.: 22 No.: 12
    DOI: https://dx.doi.org/10.3390/ijms22126186 ISSN or title: 1422-0067
  • British journal of pharmacology, Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
    Name: Miralpeix, C.; Reguera, AC.; Fosch, A.; Casas, M.; Lillo, J.; Navarro, G.; Franco, R.; Casas, J.; Alexander, S.P.H.; Casals, N; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2021
    Start page: 1507 End page: 1523 Vol.: 178 No.: 7
    DOI: https://dx.doi.org/10.1111/bph.15377 ISSN or title: 0007-1188
  • Progress in lipid research, The return of malonyl-CoA to the brain: Cognition and other stories
    Name: Fadó, R.; Rodriguez-Rodriguez, R.; Casals, N Role: Autor Publishing date: 2021
    Vol.: 81
    DOI: https://dx.doi.org/10.1016/j.plipres.2020.101071 ISSN or title: 0163-7827
  • Cell metabolism, Central ceramide signaling mediates obesity-induced precocious puberty
    Name: Heras, V.; Castellano, J.M.; Fernandois, D.; Velasco, I.; Rodríguez-Vázquez, E.; Roa, J.; Vazquez, M.J.; Ruiz-Pino, F.; Rubio, M.; Pineda, R.; Torres, E.; Avendaño, M.S.; Paredes, A.H.; Pinilla, L.; Belsham, D.D.; Diéguez, C.; Gaytán, F.; Casals, N; López, M.; Tena-Sempere, M. Role: Autor Publishing date: 2020
    Start page: 951 End page: 966 Vol.: 32 No.: 6
    DOI: https://dx.doi.org/10.1016/j.cmet.2020.10.001 ISSN or title: 1550-4131
  • Journal of cell biology, Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
    Name: Casas, M.; Fadó, R.; Domínguez, J.L.; Roig, A.; Kaku, M.; Chohnan, S.; Solé, M.; Unzeta, M.; Miñano-Molina, A.; Rodríguez, J.; Dickson, E.; Casals, N Role: Autor Publishing date: 2020
    Vol.: 219 No.: 10
    DOI: https://dx.doi.org/10.1083/jcb.201912045 ISSN or title: 0021-9525
  • Faseb journal, Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
    Name: Weber, M.; Mera, P.; Casas, J.; Salvador, J.; Rodriguez, A.; Alonso, S.; Sebastián, D.; Soler-Vázquez, M.C.; Montironi, C.; Recalde, S.; Fucho, R.; Calderón Domínguez, M.; Mir, J.; Bartrons, R.; Escolá-Gil, J.; Sánchez-Infantes, D.; Zorzano, A.; Llorente-Cortés, V.; Casals, N; Valentí, V.; Frúhbeck, G.; Herrero, L.; Serra, D. Role: Autor Publishing date: 2020
    Start page: 11816 End page: 11837 Vol.: 34 No.: 9
    DOI: https://dx.doi.org/10.1096/fj.202000678R ISSN or title: 0892-6638
  • Nanomedicine, An overview of nanomedicines for neuron targeting
    Name: Garcia-Chica, J.; Paraiso, W.; Tanabe, S.; Serra, D.; Herrero, L.; Casals, N; Garcia, J.; Ariza, X.; Quader, S.; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2020
    Start page: 1617 End page: 1636 Vol.: 15 No.: 16
    DOI: https://dx.doi.org/10.2217/nnm-2020-0088 ISSN or title: 1743-5889
  • Biochemica pharmacology, Drug uptake-based chemoresistance in breast cancer treatment
    Name: Muley, H.; Fadó, R.; Rodriguez-Rodriguez, R.; Casals, N Role: Autor Publishing date: 2020
    Vol.: 177
    DOI: https://dx.doi.org/10.1016/j.bcp.2020.113959 ISSN or title: 0006-2952
  • eNeuro, Proteasomal-Mediated Degradation of AKAP150 Accompanies AMPAR Endocytosis during cLTD
    Name: Cheng, W.; Siedlecki-Wullich, D.; Català-Solsona, J.; Fàbregas, C.; Fadó, R.; Casals, N; Solé, M.; Unzeta, M.; Saura, C.; Rodríguez, J.; Miñano-Molina, A. Role: Autor Publishing date: 2020
    Vol.: 7 No.: 2
    DOI: https://dx.doi.org/10.1523/ENEURO.0218-19.2020 ISSN or title: 2373-2822
  • eLife, Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
    Name: Palomo-Guerrero, M.; Fadó, R.; Casas, M.; Pérez-Montero, M.; Baena, M.; Helmer, PO.; Domínguez, JL.; Roig, A.; Serra, D.; Hayen, H.; Stenmark, H.; Raiborg, C.; Casals, N Role: Autor Publishing date: 2019
    Vol.: 8
    DOI: https://dx.doi.org/10.7554/eLife.51063 ISSN or title: 2050-084X
  • Biochimica et Biophysica Acta - Molecular Basis of Disease, Blood-brain barrier dysfunction underlying Alzheimer's disease is induced by an SSAO/VAP-1-dependent cerebrovascular activation with enhanced Aβ deposition
    Name: Solé, M.; Esteban, M.; Taltavull, B.; Fàbregas, C.; Fadó, R.; Casals, N; Rodríguez, J.; Miñano-Molina, A.; Unzeta, M. Role: Autor Publishing date: 2019
    Start page: 2189 End page: 2202 Vol.: 1865 No.: 9
    DOI: https://dx.doi.org/10.1016/j.bbadis.2019.04.016 ISSN or title: 1879-260X 09254439
  • Journal of lipid research, Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice
    Name: Miralpeix, C.; Fosch, A.; Casas, J.; Baena, M.; Herrero, L.; Serra, D.; Rodriguez-Rodriguez, R.; Casals, N Role: Autor Publishing date: 2019
    Start page: 1260 End page: 1269 Vol.: 60 No.: 7
    DOI: https://dx.doi.org/10.1194/jlr.M092742 ISSN or title: 0022-2275
  • Molecular Metabolism, CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
    Name: Rodriguez-Rodriguez, R.; Miralpeix, C.; Fosch, A.; Pozo Ariza, M; Calderón Domínguez, M.; Perpinyà, X.; Vellvehi, M.; López, M.; Herrero, L.; Serra, D.; Casals, N Role: Autor Publishing date: 2019
    Start page: 75 End page: 85 Vol.: 19
    DOI: https://dx.doi.org/10.1016/j.molmet.2018.10.010 ISSN or title: 2212-8778
  • Frontiers in Molecular Neuroscience, Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement
    Name: Gratacós, E.; Olivella, M.; Sánchez, N.; Yefimenko, N.; Miguez, F.; Fadó, R.; Casals, N; Gasull, X.; Ambrosio, S.; Soto, D. Role: Autor Publishing date: 2018
    Vol.: 11 No.: 275
    DOI: https://dx.doi.org/10.3389/fnmol.2018.00275 ISSN or title: 1662-5099
  • Scientific Reports, CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy
    Name: Roa, X.; Al-Atari Abou-Asi, M; Fadó, R.; Mir, J.; Muley, H.; Serra, D.; Casals, N Role: Autor Publishing date: 2018
    Vol.: 8
    DOI: https://dx.doi.org/10.1038/s41598-018-25485-7 ISSN or title: 2045-2322
  • Molecular neurobiology, Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
    Name: Mir, J.; Zagmutt, S.; Lichtenstein, M.; Casals, N; Herrero, L.; Serra, D. Role: Autor Publishing date: 2018
    Start page: 7216 End page: 7228 Vol.: 55
    DOI: https://dx.doi.org/10.1007/s12035-018-0921-3 ISSN or title: 0893-7648
  • Neuroscience, Uridine-5'-triphosphate partially partially blocks differentiation signals and favors a more repair state in cultured rat Schwann cells
    Name: Palomo-Guerrero, M.; Cosgaya, J.; Gella, A.; Casals, N; Grijota-Martinez,C. Role: Autor Publishing date: 2018
    DOI: https://dx.doi.org/10.1016/j.neuroscience.2018.01.010 ISSN or title: 0306-4522
  • Scientific Reports, Increased infammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice
    Name: Alcalá, M.; Calderón Domínguez, M.; Bustos, E.; Ramos, P.; Casals, N; Serra, D.; Viana, M.; Herrero, L. Role: Autor Publishing date: 2017
    Vol.: 7
    DOI: https://dx.doi.org/10.1038/s41598-017-16463-6 ISSN or title: 2045-2322
  • Scientific Reports, Astrocytes and oligodendrocytes in grey and white matter regions of the brain metabolize fatty acids
    Name: Hofmann, K.; Rodriguez-Rodriguez, R.; Gaebler, A.; Casals, N; Scheller, A.; Kuerschner, L. Role: Autor Publishing date: 2017
    Vol.: 7
    DOI: https://dx.doi.org/10.1038/s41598-017-11103-5 ISSN or title: 2045-2322
  • Molecular nutrition and food research, Mediterranean tomato-based sofrito protects against vascular alterations in obese Zucker rats by preserving NO bioavailability
    Name: Rodriguez-Rodriguez, R.; Jimenez-Altayo, F.; Alsina, L.; Onetti, Y.; Rinaldi de Alvarenga, J.; Claro, C.; Ogalla, E.; Casals, N; Lamuela Raventos, R. Role: Autor Publishing date: 2017
    Vol.: 61 No.: 9
    DOI: https://dx.doi.org/10.1002/mnfr.201601010 ISSN or title: 1613-4125
  • Cell metabolism, Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
    Name: Martínez Sánchez, N.; Seoane Collazo, P.; Contreras, C.; Valera, L.; Villarroya, J.; Rial Pensado, E.; Buque, X.; Aurrekoetxea, I.; Delgado, M.; Martinez Vazquez, J.; Gonzalez, R.; Roa, J.; whittle, A.; Gomez, B.; Velagapudi, V.; Loraine, Y.; Morgan, D.; Voshol, P.; Martinez de morterin, P.; Lopez, T.; Linares Pose, L.; Gonzalez, F.; Chatterjee, K.; Sobrino, T.; Medina, G.; Davis, R.; Casals, N; Oresic, M.; Coll, A.; Vidal Puig, A.; Mittag, J.; Sempere, M.; Malagon, M.; Dieguez, C.; Martinez Chantar, M.; Espichueta, P.; Rahmouni, K.; Nogueiras, R.; Sabio, G.; Villarroya, F.; López, M. Role: Autor Publishing date: 2017
    Start page: 212 End page: 229 Vol.: 26 No.: 1
    DOI: https://dx.doi.org/10.1016/j.cmet.2017.06.014 ISSN or title: 1550-4131
  • Endocrinology, Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice
    Name: Pozo Ariza, M; Rodriguez-Rodriguez, R.; Ramírez, S.; Seoane Collazo, P.; López, M.; Serra, D.; Herrero, L.; Casals, N Role: Autor Publishing date: 2017
    DOI: https://dx.doi.org/10.1210/en.2017-00151 ISSN or title: 1945-7170
  • Faseb journal, Ceramides and mitochondrial fatty acid oxidation in obesity
    Name: Fucho, R.; Casals, N; Serra, D.; Herrero, L. Role: Autor Publishing date: 2017
    Start page: 1263 End page: 1272 Vol.: 31 No.: 4
    DOI: https://dx.doi.org/10.1096/fj.201601156R ISSN or title: 0892-6638
  • Diabetes, Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity
    Name: Contreras, C.; Gonzalez, Mj.; Seoane-Collazo, P.; Casals, N; Diéguez, C.; Nogueiras, R.; López, M. Role: Autor Publishing date: 2017
    Vol.: 66 No.: 1
    DOI: https://dx.doi.org/10.2337/db15-1547 ISSN or title: 0012-1797
  • Journal of physiology and biochemistry, Abstracts of the XXXVIII Congress of the Spanish Society of Physiological Sciences (SECF), 13-16 September 2016, Zaragoza, Spain.
    Name: Palomo-Guerrero, M.; Fadó, R.; Moreno, B.; Rodríguez-Rodríguez, R.; Casals, N Role: Autor Publishing date: 2016
    Start page: S10 End page: S11
    ISSN or title: 1138-7548
  • Progress in lipid research, Carnitine palmitoyltransferase 1C: From cognition to cancer
    Name: Casals, N; Zammit, V.; Herrero, L.; Fadó, R.; Rodriguez-Rodriguez, R.; Serra, D. Role: Autor Publishing date: 2016
    Start page: 134 End page: 148 Vol.: 61
    ISSN or title: 0163-7827
  • Journal of biological chemistry, Novel Regulation of the Synthesis of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus
    Name: Fadó, R.; Soto, D.; Minano-Molina, A.; Pozo Ariza, M; Carrasco, P.; Yefimenko, N.; Rodriguez-Alvarez, J.; Casals, N Role: Autor Publishing date: 2015
    Start page: 25548 End page: 25560 Vol.: 290 No.: 42
    DOI: https://dx.doi.org/10.1074/jbc.M115.681064 ISSN or title: 0021-9258
  • JAMA Neurology, Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia
    Name: Rinaldi, C.; Schmidt, T.; Situ, A.; Johnson, J.; Lee, P.; Ke-lian, C.; Bott, L.; Fadó, R.; Harmison, G.; Parodi, S.; Grunseich, C.; Renvoise, B.; Biesecker, L.; De Michele, G.; Santorelli, F.; Filla, A.; Stevanin, G.; Duerr, A.; Brice, A.; Casals, N; Traynor, B.; Blackstone, C.; Ulmer, T.; Fischbeck, K. Role: Autor Publishing date: 2015
    Start page: 561 End page: 570 Vol.: 72 No.: 5
    DOI: https://dx.doi.org/10.1001/jamaneurol.2014.4769 ISSN or title: 2168-6149
  • American journal of physiology. Endocrinology and metabolism, Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
    Name: Malandrino, M.; Fucho, R.; Weber, M.; Calderón Domínguez, M.; Mir, J.; Valcarcel, L.; Escote, X.; Gómez Serrano, M.; Peral, B.; Salvado, L.; Fernández Veledo, S.; Casals, N; Vázquez-Carrera, M.; Villarroya, F.; Vendrell, J.; Serra, D.; Herrero, L. Role: Autor Publishing date: 2015
    Vol.: 308 No.: 9
    DOI: https://dx.doi.org/10.1152/ajpendo.00362.2014 ISSN or title: 0193-1849
  • Cell Reports, Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance
    Name: Contreras, C.; González García, I.; Martínez Sánchez, N.; Seoane Collazo, P.; Jacas Mateu, J; Morgan, D.; Serra, D.; Gallego, R.; González, F.; Casals, N; Nogueiras, R.; Rahmouni, K.; Dieguez, C.; López, M. Role: Autor Publishing date: 2014
    Start page: 366 End page: 377 Vol.: 9 No.: 1
    DOI: https://dx.doi.org/10.1016/j.celrep.2014.08.057 ISSN or title: 2211-1247
  • Diabetes, Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin
    Name: Gao, S.; McMillan, R.; Jacas Mateu, J; Zhu, Q.; Li, X.; Kumar, G.; Casals, N; Hegardt, F.; Robbins, P.; Lopaschuk, G.; Hulver, M.; Butler, A. Role: Autor Publishing date: 2014
    Start page: 3242 End page: 3252 Vol.: 63 No.: 10
    DOI: https://dx.doi.org/10.2337/db14-0388 ISSN or title: 0012-1797
  • PLoS One, Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation
    Name: Lamarca, A.; Gella, A.; Martiañez, T.; Segura, M.; Figueiro, J.; Grijota-Martinez,C.; Trullas, R.; Casals, N Role: Autor Publishing date: 2014
    Vol.: 9 No.: 6
    DOI: https://dx.doi.org/10.1371/journal.pone.0098998 ISSN or title: 1932-6203
  • The journal of biological chemistry (Versió web), Defective in Mitotic Arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation.
    Name: Hernández-Ortega, S; Bru, S.; Ricco, N.; Ramírez, S.; Casals, N; Jiménez, J.; Isasa, M.; Crosas, B.; Clotet, J. Role: Autor Publishing date: 2013
    Start page: 4704 End page: 4714 Vol.: 288 No.: 7
    DOI: https://dx.doi.org/10.1074/jbc.M112.426593 ISSN or title: 1083-351X
  • Purinergic Signalling, N-cadherin expression is regulated by UTP in schwannoma cells
    Name: Martiáñez, T.; Lamarca, A.; Casals, N; Gella, A. Role: Autor Publishing date: 2013
    Start page: 259 End page: 270 Vol.: 9
    ISSN or title: 1573-9538
  • Diabetes, hypothalamic ceramide levels regulated by CPTC1C mediate the oxigenic effect of ghrelin
    Name: Ramírez, S.; Martins, L.; Jacas Mateu, J; Carrasco, P.; Pozo Ariza, M; Clotet, J.; Serra, D.; Hegardt , FG.; Diéguez, C.; López, M.; Casals, N Role: Autor Publishing date: 2013
    Start page: 2329 End page: 2337 Vol.: 62
    DOI: https://dx.doi.org/10.2337/db12-1451 ISSN or title: 0012-1797
  • Physiology and behavior, Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei
    Name: Gao, S.; Casals, N; keung, W.; Moran, TH.; Lopaschuk, GD. Role: Autor Publishing date: 2013
    Start page: 165 End page: 170 Vol.: 118
    ISSN or title: 0031-9384
  • Behavioural brain research, Carnitine palmitoyltransferase 1C deficiency causes motor impairment and hypoactivity.
    Name: Carrasco, P.; Jacas Mateu, J; Sahún, I.; Muley, H.; Ramírez, S.; Puisac , B.; Mezquita, Pau; Pié, J.; Dierssen , M.; Casals, N Role: Autor Publishing date: 2013
    Start page: 291 End page: 297 Vol.: 256
    DOI: https://dx.doi.org/10.1016/j.bbr.2013.08.004 ISSN or title: 0166-4328
  • Journal of lipid research, Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
    Name: Arnedo, M.; Menao, S.; Puisac, B.; Teresa-Rodrigo, ME; Maria, E.; Gil-Rodríguez, M.; Maria, C.; López-Viñas, E.; Gómez-Puertas, P.; Casals, N; Casale, Cesar H.; Hegardt , FG. Role: Autor Publishing date: 2012
    Start page: 2046 End page: 2056 Vol.: 53 No.: 10
    DOI: https://dx.doi.org/10.1194/jlr.M025700 ISSN or title: 0022-2275
  • Mol Biol Rep, Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway.
    Name: Puisac, B.; Ramos, M.; Arnedo, M.; Menao, S.; Gil-Rodríguez, M.; Teresa-Rodrigo, ME; Pié, A.; de Karam, JC; Wesselink, JJ; Giménez, I.; Ramos, FJ; Casals, N; Gómez-Puertas, P.; Hegardt , FG.; Pié, J. Role: Autor Publishing date: 2012
    Start page: 4777 End page: 4785 Vol.: 39
  • Journal of biological chemistry, Ceramide levels regulated by carnitine palmitoyl transferase 1C control dendritic spine maturation and cognition.
    Name: Carrasco, P.; Sahún, I.; McDonald, J.; Ramírez, S.; Jacas Mateu, J; Gratacós, E.; Sierra, AY; Serra, D.; Herrero, L.; Acker-Palmer, A.; Hegardt , FG.; Dierssen , M.; Casals, N Role: Autor Publishing date: 2012
    ISSN or title: 0021-9258
  • Journal of Cell Science, Dental Pulp of the Third Molar: A New Source of Pluripotent-like Stem Cells.
    Name: Al-Atari Abou-Asi, M; Gil-Recio, C.; Fabregat, M.; García-Fernández, DA.; Barajas, M.; Carrasco, M.; Jung, H.; Hernandez Alfaro, F; Casals, N; Prósper, F.; Ferrés, E.; Giner Tarrida, L Role: Autor Publishing date: 2012
    Start page: 3343 End page: 3356 Vol.: 125 No.: 14
    DOI: https://dx.doi.org/10.1242/jcs.096537 ISSN or title: 0021-9533
  • Neuroscience and Medicine, A Nucleotide-Based Drug Protects against Glutamate- and MPP+-Induced Neurotoxicity
    Name: Gella, A.; Martiañez, T.; Lamarca, A.; Gutierrez, C.; Durany, N.; Casals, N Role: Autor Publishing date: 2011
    Start page: 154 End page: 160 Vol.: 2
    DOI: https://dx.doi.org/10.4236/nm.2011.22022
  • American journal of physiology. Regulatory integrative and comparative physiology, Malonyl-CoA Mediates Leptin Hypothalamic Control of Feeding Independent of Inhibition of CPT-1a.
    Name: Gao, S.; keung, W.; Serra, D.; Wang, W.; Carrasco, P.; Casals, N; Hegardt , FG.; Moran, TH.; Lopaschuk, GD. Role: Autor Publishing date: 2011
    Start page: 209 End page: 217 Vol.: 301
    ISSN or title: 0363-6119
  • Histology and histopathology, Isolation of pluripotent stem cells from human third molar dental pulp
    Name: Al-Atari Abou-Asi, M; Barajas, M.; Hernandez Alfaro, F; Gil-Recio, C.; Fabregat, M.; Ferrés, E.; Giner Tarrida, L; Casals, N Role: Autor Publishing date: 2011
    Start page: 1057 End page: 1070 Vol.: 26
    DOI: https://dx.doi.org/10.14670/HH-26.1057 ISSN or title: 0213-3911
  • Proceedings of the National Academy of Sciences of the United States of America, Important Roles for Brain-specific Carnitine Palmitoyltransferase and Ceramide Metabolism in Leptin Hypothalamic Control of Feeding
    Name: Gao, S.; Zhu, G.; Gao, X.; Wu, D.; Carrasco, P.; Casals, N; keung, W.; Hegardt , FG.; Moran, TH.; Lopaschuk, GD. Role: Autor Publishing date: 2011
    Start page: 9691 End page: 9696 Vol.: 108
    ISSN or title: 0027-8424
  • Journal of inherited metabolic disease, Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria
    Name: Puisac, B.; Arnedo, M.; Casale, Cesar H.; Ribate, MP; Castiella, T.; Ramos, FJ; Ribes, A.; Pérez-Cerdá, C.; Casals, N; Hegardt , FG.; Pié, J. Role: Autor Publishing date: 2010
    Start page: 405 End page: 410 Vol.: 33 No.: 4
    DOI: https://dx.doi.org/10.1007/s10545-010-9097-3 ISSN or title: 0141-8955
  • Tissue engineering. Part A, tissue engineering, Buccal fat pad, an oral access-source of human adipose stem cells with potential for osteochondral tissue engineering, an in vitro study
    Name: Ferre, E.; Martí, C.; Hernandez Alfaro, F; Klein-Nulend, J.; Casals, N Role: Autor Publishing date: 2010
    Start page: 1083 End page: 1095 Vol.: 16 No.: 5
    DOI: https://dx.doi.org/10.1089/ten.TEC.2009.0487 ISSN or title: 1937-3341
  • American Journal of Medical Genetics A, Mutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndrome.
    Name: Pié, J.; Gil-Rodríguez, M.; Ciero, M.; López-Viñas, E.; Ribate, MP; Arnedo, M.; Deardorff, M.; Puisac, B.; Legarreta, J.; de Karam, JC; Egío, E.; Bueno, I.; Baldellou, A.; Calvo, MT; Casals, N; Olivares, JL; Losada, A.; Hegardt , FG. Role: Autor Publishing date: 2010
    Start page: 924 End page: 929 Vol.: 152A
    ISSN or title: 1552-4833
  • Human mutation, Ten Novel HMGCL Mutations in 24 Patients of Different Origin with 3-Hydroxy-3-Methyl-Glutaric Aciduria
    Name: Menao, S.; López-Viñas, E.; Flores-Mir, C.; Puisac, B.; Gratacós, E.; Arnedo, M.; Carrasco, P.; Serra, D.; Asins, G.; Ramos, FJ; Gómez-Puertas, P.; Hegardt , FG.; Casals, N; Pié, J. Role: Autor Publishing date: 2009
    Start page: 520 End page: 529 Vol.: 3
    ISSN or title: 1059-7794
  • Journal of biological chemistry, CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
    Name: Sierra, A.; Gratacós, E.; Carrasco, P.; Clotet, J.; Ureña, J.; Serra, D.; Asins, G.; Hegardt, F.; Casals, N Role: Autor Publishing date: 2008
    Start page: 6878 End page: 6885 Vol.: 283 No.: 11
    DOI: https://dx.doi.org/10.1074/jbc.M707965200 ISSN or title: 0021-9258
  • Analytica chimica acta, A new lc-esi-ms/ms method to measure acylcarnitine levels in cultured cells
    Name: Casals, N Role: Autor Publishing date: 2007
    Start page: 1 End page: 6 Vol.: 599
    ISSN or title: 0003-2670
  • Molecular genetics and metabolism, Molecular genetics of HMG-CoA lyase deficiency
    Name: Casals, N Role: Autor Publishing date: 2007
    Start page: 198 End page: 209 Vol.: 92
    ISSN or title: 1096-7192
  • Molecular genetics and metabolism, C-Terminal end amd aminoacid Lys48in HMG-CoA lyase are involved in substrate binding and enzyme activity.
    Name: Casals, N Role: Autor Publishing date: 2007
    Start page: 120 End page: 127 Vol.: 91
    ISSN or title: 1096-7192
  • Journal of inherited metabolic disease, Refining the diagnosis of mitochondrial HMG-CoA synthase deficiency
    Name: Casals, N Role: Autor Publishing date: 2006
    Start page: 207 End page: 211 Vol.: 29
    ISSN or title: 0141-8955
  • Journal of inherited metabolic disease, A single residue mutation, G203E, causes 3-hydroxy-3-methylglutaric aciduria by occluding the substrate channel in the 3D structural model of HMG-CoA lyase
    Name: Casals, N Role: Autor Publishing date: 2006
    Start page: 64 End page: 70 Vol.: 29
    ISSN or title: 0141-8955
  • Biophysical chemistry, Skipping of exon 2 and exon 2 plus 3 of HMG-CoA lyase (HL) gene produce the loss of beta sheet 1 and 2 at the recently proposed (beta-alfa)8 TIM barrel model of HL.
    Name: Casals, N Role: Autor Publishing date: 2005
    Start page: 241 End page: 245 Vol.: 115
    ISSN or title: 0301-4622
  • Journal of biological chemistry, Structural (beta alpha)(8) TIM barrel model of 3-hydroxy-3-methylglutaryl-coenzyme A lyase
    Name: Casals, N; Gómez-Puertas, P.; Pié, J.; Mir, C.; Roca, R.; Puisac, B.; Aledo, R.; Clotet, J.; Menao, S.; Serra, D.; Asins, G.; Till, J.; Alun, C.; Jones, E.; Cresto, Juan C.; Chamoles, Nestor A; Abdenur, Jose E; Mayatepek, E.; Besley, G.; Valencia, A.; Hegardt , FG. Role: Autor Publishing date: 2003
    Start page: 29016 End page: 29023 Vol.: 278 No.: 31
    DOI: https://dx.doi.org/10.1074/jbc.M304276200 ISSN or title: 0021-9258
  • Journal of physiology and biochemistry, Molecular basis of 3-hydroxy 3-methylglutaric aciduria
    Name: Casals, N Role: Autor Publishing date: 2003
    Start page: 311 End page: 322 Vol.: 59
    ISSN or title: 1138-7548
  • Journal of biological chemistry, Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition
    Name: Morillas, M.; Bentebibel, A.; Selles, E.; Casals, N; Valencia, A.; Hegardt , FG.; Asins, G.; Serra, D.; Gómez-Puertas, P. Role: Autor Publishing date: 2003
    Start page: 9058 End page: 9063 Vol.: 278
    ISSN or title: 0021-9258
  • Yeast, Identification of multicopy supressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.
    Name: Muñoz, I.; Simón, E.; Casals, N; Clotet, J.; Ariño, J. Role: Autor Publishing date: 2003
    Start page: 157 End page: 169 Vol.: 30
    ISSN or title: 0749-503X
  • Journal of molecular neuroscience, CDP-choline prevents glutamate-mediated cell death in cerebellar granule neurons
    Name: Mir, C.; Clotet, J.; Aledo, R.; Durany, N.; Argemí Renom, J; Lozano, R.; Cervós-Navarro, J.; Casals, N Role: Autor Publishing date: 2003
    Start page: 53 End page: 59 Vol.: 20
    ISSN or title: 0895-8696
  • Journal of pediatrics, Diagnosing mitochondrial HMG-CoA synthase deficiency
    Name: Casals, N Role: Autor Publishing date: 2002
    Start page: 778 End page: 780 Vol.: 140
    ISSN or title: 0022-3476
  • Human genetics, The genetic basis of mitochondrial HMG-CoA synthase deficiency
    Name: Casals, N Role: Autor Publishing date: 2001
    Start page: 19 End page: 23 Vol.: 109
    ISSN or title: 0340-6717
  • Insect molecular biology, 3-hydroxy-3-methylglutaryl CoA synthase-1 of Blattella germanica has structural and functional features of an active retrogene
    Name: Casals, N Role: Autor Publishing date: 2001
    Start page: 837 End page: 743 Vol.: 31
    ISSN or title: 0962-1075
  • Archives of biochemistry and biophysics, A nonsense mutation in the exon 2 of the 3-hydroxy-3-methylglutaryl CoA lyase (HL) gene producing three mature mRNAs is the main cause of 3-hydroxy-3-methylglutaric aciduria in european mediterranean patients
    Name: Casals, N Role: Autor Publishing date: 1998
    Vol.: 349
    ISSN or title: 0003-9861
  • Archives of biochemistry and biophysics, Two missense point mutations in different alleles in the 3-hydroxy-3-methylglutaryl Coenzyme A Lyase gene produce 3-hydroxy-3methylglutaric aciduria in a french patient
    Name: Casals, N Role: Autor Publishing date: 1998
    Start page: 197 End page: 203 Vol.: 358
    ISSN or title: 0003-9861
  • Journal of lipid research, A two-base deletion in exon 6 of the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene producing the skipping of exons 5 and 6 determines 3-hydroxy-3-methylglutaric aciduria
    Name: Casals, N Role: Autor Publishing date: 1997
    Start page: 90 End page: 100 Vol.: 38
    ISSN or title: 0022-2275
  • Biochemica journal, A nonsense mutation in the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene produces exon-skipping in two patiens of different origin with hl deficiency
    Name: Casals, N Role: Autor Publishing date: 1997
    Start page: 329 End page: 335 Vol.: 323
    ISSN or title: 0264-6021
  • Physiological entomology, Expression and activity of 3-hydroxy-3-methylglutaryl-CoA synthase and reductase in the fat body of ovariectomized and allatectomized Blattella germanica
    Name: Casals, N Role: Autor Publishing date: 1997
    Start page: 6 End page: 12 Vol.: 22
    ISSN or title: 0307-6962
  • Gaceta sanitaria, La prescripción farmacéutica en Catalunya tras el decreto de financiación selectiva de medicamentos
    Name: Casals, N Role: Autor Publishing date: 1996
    Start page: 183 End page: 190 Vol.: 10
    ISSN or title: 0213-9111
  • Insect molecular biology, Coordinated Expression and Activity of 3-hydroxy-3-methylglutaryl CoA synthase and reductase in the fat body of Blattella germanica during vitellogenesis
    Name: Casals, N Role: Autor Publishing date: 1996
    Start page: 837 End page: 843 Vol.: 26
    ISSN or title: 0962-1075
  • Journal of lipid research, An aberrant splicing by a point mutation and a deletion in 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene produce an hereditary hl deficiency
    Name: Casals, N Role: Autor Publishing date: 1996
    Start page: 2420 End page: 2431 Vol.: 37
    ISSN or title: 0022-2275
  • Journal of biological chemistry, Blattella germanica Has Two HMG-CoA Synthase Genes. Both Are Regulated In The Ovarian Development
    Name: Casals, N Role: Autor Publishing date: 1994
    Start page: 11707 End page: 11713 Vol.: 269
    ISSN or title: 0021-9258
  • Archives of biochemistry and biophysics, Regulation of Mitochondrial 3-Hydroxy-3-Methylglutaryl-coenzime A Synthase Protein by Starvation, Fat Feeding and Diabetes
    Name: Casals, N Role: Autor Publishing date: 1993
    Start page: 40 End page: 45 Vol.: 307
    ISSN or title: 0003-9861
  • Biochemica journal, Regulation of the expression of the mitochondrial 3-hidroxy-3-methylglutaryl-CoA synthase gene
    Name: Casals, N Role: Autor Publishing date: 1992
    Vol.: 283
    ISSN or title: 0264-6021
  • El DNA es pot manipular.
    Publishing date: 2008
  • PLURIPOTENT STEM CELLS OBTAINED FROM DENTAL PULP
    Owner: Al-Atari Abou-Asi, M; Casals, N; Giner Tarrida, L; Ferrés, E.
    Property type: Altres Application number: DSM ACC3002 Application date: 21/07/2010
    Description: Pais prioritat: España Paisos: Europa y Estados Unidos (US 9.017.663 B2) date: 28/04/2015
  • Células madre pluripotenciales obtenidas a partir de la pulpa dental
    Owner: Al-Atari Abou-Asi, M; Casals, N; Ferrés, E.; Giner Tarrida, L
    Property type: Altres Application number: P200930488 Application date: 21/07/2009
    Description: REGENERAR TEJIDO OSEO. LA PRESENTE INVENCION SE REFIERE A LAS CELULAS MADRE PLURIPOTENTES OBTENIDAS A PARTIR DE LA PULPA DENTAL DE PACIENTES DE DIFERENTES EDADES, LA INVENCION COMPRENDE ADEMAS CULTIVOS DE DICHAS CELULAS, LOS MEDIOS PARA SU OBTENCION Y COMPOSICIONES FARMACEUTICAS QUE LOS COMPRENDEN, ASI COMO SU APLICACION EN LA REGENERACION DE LOS TEJIDOS.
  • Células madre mesenquimales, procedimiento de obtención y uso de estas
    Owner: Casals, N; Martí, C.; Farré, E.
    Property type: Altres Application number: P 200803111 Application date: 01/01/1900
    Description: Pais prioritat: Espanya
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Humanities and Cultural Studies
    • - Theory of Knowledge
    Bachelor's Degree in Nursing
    • - Surgical and Critical Care Nursing
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Pharmacology
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Surgical and Critical Care Nursing
  • Official Master
    Master's Degree in Research in Dentistry
    • - Basic Pharmacology
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Surgical and Critical Care Nursing
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
  • Others
    Programa Gaudí de Formació del Professorat 18 - 19
    • - Mòdul 3 Recerca i Innovació
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
  • Official Master
    Master's Degree in Research in Dentistry
    • - Pre-Clinical and Clinical Pharmacology
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
  • Official Master
    Master's Degree in Research in Dentistry
    • - Farmacologia Preclínica y Clínica
    • - Pre-Clinical and Clinical Pharmacology
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
  • Official Master
    Master's Degree in Research in Dentistry
    • - Pre-Clinical and Clinical Pharmacology
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2012-2013 - Period: 01/09/2012 - 31/08/2013
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Regenerative Medicine and Use of Haematopoietic Progenitor Cells
  • Official Master
    University Master's degree in Basic Dentistry Research and Biomedicine
    • - Actualitat de la Recerca en Odontologia
    • - Bioinformatics
    • - Final Master's Project
Course 2011-2012 - Period: 01/09/2011 - 31/08/2012
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Cellular Therapy and Regenerative Medicine. Bone Marrow, Organ and Tissue Transplant
    • - Pharmacology
    • - Regenerative Medicine: Drug Therapy in Organ Transplants
  • Official Master
    University Master's Degree in Basic Dentistry Research and Biomedicine
    • - Bioinformatics
    • - Current Dentistry Research
    • - Final Master's Project
    • - Research Protocol
    • - Molecular and Cell Biology Techniques
Course 2010-2011 - Period: 01/09/2010 - 31/08/2011
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
  • Official Master
    University Master's Degree in Basic Dentistry Research and Biomedicine
    • - Informatic Tools for Biomedicine
    • - Actualitat de la Recerca en Odontologia
    • - Final Master's Degree Project
    • - Protocol de Recerca
Course 2009-2010 - Period: 01/09/2009 - 31/08/2010
  • Official Master
    University Master's Degree in Basic Dentistry Research and Biomedicine
    • - Patologia Mol·lecular
    • - Protocol de Recerca
  • Degree
    Degree in Dentistry
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 2008-2009 - Period: 01/09/2008 - 31/08/2009
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
  • Official Master
    University Master's degree in Basic Dentistry Research and Biomedicine
    • - Proyecto de Investigación 3
    • - Actualidad de la Investigación en Odontología
    • - Informatic Tools for Biomedicine
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 2007-2008 - Period: 01/09/2007 - 31/08/2008
  • Official Master
    University Master's degree in Basic Dentistry Research and Biomedicine
    • - Proyecto de Investigación 1
    • - Técnicas Avanzadas en Biología Molecular, Celular y Microscopía
  • Degree
    Degree in Dentistry
    • - Pharmacology
Course 2006-2007 - Period: 01/09/2006 - 31/08/2007
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Prácticas de Laboratorio de Investigación Biomédica
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 2005-2006 - Period: 01/09/2005 - 31/08/2006
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Microbiology
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Nutrition and Dietetics
    • - Pharmacology
Course 2004-2005 - Period: 01/09/2004 - 31/08/2005
  • PhD
    Doctorado para Profesionales en Atención Primaria
    • - Bases moleculares del diagnóstico precoz
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Prácticas de Laboratorio de Investigación Biomédica
    • - Microbiology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - Nutrition and Dietetics
    • - Pharmacology
Course 2003-2004 - Period: 01/09/2003 - 31/08/2004
  • PhD
    Doctorado para Profesionales en Atención Primaria
    • - Bases moleculares del diagnóstico precoz
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Microbiology
    • - Prácticas de Laboratorio de Investigación Biomédica
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Nutrition and Dietetics
    • - Pharmacology
Course 2002-2003 - Period: 01/09/2002 - 31/08/2003
  • PhD
    Doctorado para Profesionales en Atención Primaria
    • - Bases moleculares del diagnóstico precoz
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Pharmacology
    • - Microbiology
    • - Prácticas de Laboratorio de Investigación Biomédica
  • Diploma
    Diploma in Nursing
    • - Pharmacology
    • - Nutrition and Dietetics
Course 2001-2002 - Period: 01/09/2001 - 31/08/2002
  • PhD
    Doctorado para Profesionales de Atención Primaria
    • - Bases moleculares del diagnóstico y la prevención de la enfermedad
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
  • Others
    Introduction Course in Health Sciences
    • - Biology 1
Course 2000-2001 - Period: 01/09/2000 - 31/08/2001
  • PhD
    Doctorado para Profesionales de Atención Primaria
    • - Bases moleculares del diagnóstico y la prevención de la enfermedad
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 1999-2000 - Period: 01/09/1999 - 31/08/2000
  • Degree
    Degree in Dentistry
    • - Molecular and Cell Biology
    • - Advanced Cell Biology
    • - Advanced Molecular Biology
Course 1998-1999 - Period: 01/09/1998 - 31/08/1999
  • Degree
    Degree in Dentistry
    • - Molecular and Cell Biology
    • - Advanced Cell Biology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - The Human Body 1
    • - The Normal Functions of the Human Body
Course 1997-1998 - Period: 01/09/1997 - 31/08/1998
  • Degree
    Degree in Dentistry
    • - Advanced Cell Biology
    • - Molecular and Cell Biology
    • - Advanced Molecular Biology
  • Others
    Complementary Formation in Dentistry
    • - Biología Molecular y Celular
    Introduction Course in Health Sciences
    • - Metodología Científica Aplicada a la Biología 1
    • - Metodología Científica Aplicada a la Biología 2
    • - Biología Celular y Molecular 1

Academic training

  • Doctora en Farmàcia
  • Universitat de Barcelona
  • Master en Economia de la Salut i Gestió Sanitària
  • Universitat de Barcelona/Universitat Pompeu Fabra
  • Farmàcia
  • Universitat de Barcelona

Projects

Competitive

Non-competitive

  • EXPLORANDO LA RELEVANCIA DE LA INTERACCION DE CPT1C CON OTRAS PROTEINAS EN LA REGULACION DE LA HOMEOSTASIS ENERGETICA Y EL DESARROLLO DE LA OBESIDAD
    PI: Casals, N; Rodriguez-Rodriguez, R. Start date: 01/09/2021 End date: 31/08/2024
    Financing entity: Ministerio de Ciencia e Innovación (MICINN)
  • Administracion de fármacos específicos de la CPT1 central: una novedosa estrategia basada en nanomedicina para combatir obesidad y cáncer
    PI: Rodriguez-Rodriguez, R. Start date: 01/01/2019 End date: 31/12/2021
    Financing entity: MINISTERIO DE CIENCIA E INNOVACION Financing entity code: PCI2018-092997
  • Cpt1c en el hipotálamo ventromedial como nueva diana terapéutica en la regulación del balance energético: mecanismos moleculares implicados
    PI: Casals, N; Rodriguez-Rodriguez, R. Start date: 01/01/2018 End date: 31/12/2020
    Financing entity: Ministerio de Economía, Industria y Competitividad Financing entity code: SAF2017-83813-C3-3-R
  • Carnitine palmitoyltransferase 1-mediated strategies to activate brown fat and reduce food intake to fight against obesity
    PI: Casals, N; Serra, D. Start date: 01/03/2017 End date: 01/03/2020
    Financing entity: Fundació la Marató de TV3 Financing entity code: 201627-31
  • Regulation of Lipid Metabolism in Obesity and Diabetes (METALIP)
    PI: Casals, N Start date: 01/01/2017 End date: 31/12/2019
    Financing entity: Agencia de Gestió d'ajudas Universitaries Investigació AGAUR Financing entity code: 2017 SGR 278
  • Papel de la carnitina pamitoil transferasa 1C como sensor hipotalámico de aciles-CoA y regulador del metabolismo periférico de los lípidos (SAF2014-52223-C2-2-R)
    PI: Casals, N Start date: 01/01/2015 End date: 31/12/2017
    Financing entity: Ministerio de Ciencia e Innovación (MICINN) Financing entity code: SAF2014-52223-C2-2-R
  • Searching new biomarkers and therapeutic targets related to cognitive deficits in early stages of Alzheimer's Disease: Role of AKAP79/150, CPT1C and SSAO/VAP-1 in Abmediated AMPAR dysfunction.
    PI: Casals, N; Rodríguez , J. Start date: 01/01/2015 End date: 31/12/2017
    Financing entity: Fundació la Marató de TV3
  • Participación de CPT1C en la síntesis de ceramidas y el control de la ingesta alimentaria
    PI: Casals, N Start date: 01/01/2012 End date: 31/12/2014
    Financing entity: Ministerio de Economía y Competitividad Financing entity code: SAF2011- 30520- c02-02
  • Homeostasi Energètica
    PI: Casals, N Start date: 26/11/2009 End date: 31/12/2014
    Financing entity: Generalitat de Catalunya Financing entity code: 2009 SRG 1376
  • Bases moleculars de acción de las carnitina aciltransferasas como reguladoras de la oxidación de las grasas y su papel en la obesidad, la resistencia a la insulina y el apetito
    PI: Hegardt , FG. Start date: 01/01/2008 End date: 31/12/2012
    Financing entity: Ministerio de Ciencia y Tecnología Financing entity code: SAF2007-61926
  • Càtedra cultura, ciència i religió
    PI: Corcó, Josep Start date: 01/09/2013 End date: 31/08/2016
    Financing entity: FUNDACIÓ BARCELONA I FAMÍLIA
  • Efecto del Nucleo CMP Forte en la regeneración neuronal del Sistema Nervioso Periférico
    PI: Casals, N Start date: 01/05/2011 End date: 01/05/2012
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Neuroprotección del núcleo CMP forte en células nerviosas
    PI: Casals, N Start date: 01/01/2006 End date: 31/12/2007
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Estudio del papel neuroprotector de la CDP-colina en la muerte neuronal inducida por el péptido beta-amiloide y el NO
    PI: Casals, N Start date: 01/01/2002 End date: 31/12/2003
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional
  • Estudio del papel de la CDP-colina en la reducción de la apopotosis neuronal inducida por excitotoxicidad
    PI: Casals, N Start date: 01/01/1999 End date: 31/12/2000
    Financing entity: Laboratorios Farmacéuticos Ferrer-Internacional

Publications

Articles

Books

  • Biology of Sex Differences, CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst
    Name: Zagmutt, S.; Mera, P.; González, I.; Ibeas, K.; Romero, M.; Obri, A.; Martin, B.; Esteve, A.; Soler-Vázquez, M.C.; Bastias, M.; Cañes, L.; Augé, E.; Pelegri, C.; Vilaplana, J.; Ariza, X.; García, J.; Martinez, J.; Casals, N; López, M.; Palmiter, R.; Sanz, E.; Quintana, A.; Herrero, L.; Serra, D. Role: Autor Publishing date: 2023
    Vol.: 14 No.: 1
    DOI: https://dx.doi.org/10.1186/s13293-023-00498-8 ISSN or title: 2042-6410
  • Metabolic engineering, Implantation of CPT1AM-expressing adipocytes reduces obesity and glucose intolerance in mice
    Name: Soler-Vázquez, M.C.; Romero, M.; Todorcevic, M.; Delgado, K.; Calatayud, C.; Benitez, A.; La Chica, M.; Mera, P.; Zagmutt, S.; Bastías, M.; Ibeas, K.; Casals, N; Escolà, J.; Llorente-Cortés, V.; Consiglio, A.; Serra, D.; Herrero, L. Role: Autor Publishing date: 2023
    Start page: 256 End page: 272 Vol.: 77
    DOI: https://dx.doi.org/10.1016/j.ymben.2023.04.010 ISSN or title: 1096-7176
  • Journal of Physiology, CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non-associative learning
    Name: Iborra, G.; Djebari, S.; Sánchez, I.; Gratacòs, E.; Sánchez, N.; Radošević, M.; Casals, N; de Dios, J.; Soto, D.; Jiménez, L. Role: Autor Publishing date: 2023
    Start page: 3533 End page: 3556 Vol.: 601 No.: 16
    DOI: https://dx.doi.org/10.1113/JP284248 ISSN or title: 1469-7793
  • European journal of neuroscience, XIth Cajal Conference: New frontiers in neuron-glial plasticity in health and disease
    Name: Louail, A.; Bengoetxea, I.; Rojas, R.; Casals, N Role: Autor Publishing date: 2023
    Start page: 1447 End page: 1465 Vol.: 57 No.: 9
    DOI: https://dx.doi.org/10.1111/ejn.15960 ISSN or title: 0953-816X
  • Biomaterials science, Nanomedicine targeting brain lipid metabolism as a feasible approach for controlling the energy balance
    Name: Garcia, J.; Paraiso, W.; Zagmutt, S.; Fosch, A.; Reguera, AC.; Alzina, S.; Sánchez, L.; Fukushima, S.; Toh, K.; Casals, N; Serra, D.; Herrero, L.; Garcia, J.; Kataoka, K.; Ariza, X.; Quader, S.; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2023
    Start page: 2336 End page: 2347 Vol.: 11
    DOI: https://dx.doi.org/10.1039/d2bm01751b ISSN or title: 2047-4830
  • JOURNAL OF NEUROENDOCRINOLOGY, Targeting carnitine palmitoyltransferase 1 isoforms in the hypothalamus: A promising strategy to regulate energy balance
    Name: Rodriguez-Rodriguez, R.; Fosch, A.; Garcia, J.; Zagmutt, S.; Casals, N Role: Autor Publishing date: 2023
    Vol.: 35 No.: 9
    DOI: https://dx.doi.org/10.1111/jne.13234 ISSN or title: 1365-2826
  • Cell death and disease, To be or not to be a fat burner, that is the question for cpt1c in cancer cells
    Name: Fadó, R.; Zagmutt, S.; Herrero, L.; Muley, H.; Rodriguez-Rodriguez, R.; Bi, H.; Serra, D.; Casals, N Role: Autor Publishing date: 2023
    Vol.: 14 No.: 1
    DOI: https://dx.doi.org/10.1038/s41419-023-05599-1 ISSN or title: 2041-4889
  • International Journal of Molecular Sciences, Central Regulation of Brown Fat Thermogenesis in Response to Saturated or Unsaturated Long-Chain Fatty Acids
    Name: Fosch, A.; Rodriguez, M.; Miralpeix, C.; Zagmutt, S.; Larrañaga, M.; Reguera, AC.; Garcia, J.; Herrero, L.; Serra, D.; Casals, N; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2023
    Vol.: 24 No.: 2
    DOI: https://dx.doi.org/10.3390/ijms24021697 ISSN or title: 1422-0067
  • International Journal of Molecular Sciences, Cpt1c Downregulation Causes Plasma Membrane Remodelling and Anthracycline Resistance in Breast Cancer
    Name: Muley, H.; Valencia, K.; Casas, J.; Moreno, B.; Botella, L.; Lecanda, F.; Fadó, R.; Casals, N Role: Autor Publishing date: 2023
    Vol.: 24 No.: 2
    DOI: https://dx.doi.org/10.3390/ijms24020946 ISSN or title: 1422-0067
  • Nutrients, Feeding the Brain: Effect of Nutrients on Cognition, Synaptic Function, and AMPA Receptors
    Name: Fadó, R.; Molins, A.; Rojas, R.; Casals, N Role: Autor Publishing date: 2022
    Vol.: 14 No.: 19
    DOI: https://dx.doi.org/10.3390/nu14194137 ISSN or title: 2072-6643
  • Cellular and molecular life sciences, Hypothalamic endocannabinoids in obesity: an old story with new challenges
    Name: Miralpeix, C.; Reguera, AC.; Fosch, A.; Zagmutt, S.; Casals, N; Cota, D.; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2021
    Start page: 7469 End page: 7490 Vol.: 78 No.: 23
    DOI: https://dx.doi.org/10.1007/s00018-021-04002-6 ISSN or title: 1420-682X
  • Biomaterials science, Poly-ion complex micelles effectively deliver CoA-conjugated CPT1A inhibitors to modulate lipid metabolism in brain cells
    Name: Paraiso, W.; Garcia, J.; Ariza, J.; Zagmutt, S.; Fukushima, S.; Garcia, J.; Mochida, Y.; Serra, D.; Herrero, L.; Kinoh, H.; Casals, N; Kataoka, K.; Rodriguez-Rodriguez, R.; Quader, S. Role: Autor Publishing date: 2021
    Start page: 7076 End page: 7091 Vol.: 9 No.: 21
    DOI: https://dx.doi.org/10.1039/d1bm00689d ISSN or title: 2047-4830
  • International Journal of Molecular Sciences, Identification of the ghrelin and cannabinoid cb2 receptor heteromer functionality and marked upregulation in striatal neurons from offspring of mice under a high-fat diet
    Name: Lillo, J.; Lillo, A.; Zafra, D.A.; Miralpeix, C.; Rivas-Santisteban, R.; Casals, N; Navarro, G.; Franco, R. Role: Autor Publishing date: 2021
    Vol.: 22 No.: 16
    DOI: https://dx.doi.org/10.3390/ijms22168928 ISSN or title: 1422-0067
  • International Journal of Molecular Sciences, New insights of sf1 neurons in hypothalamic regulation of obesity and diabetes
    Name: Fosch, A.; Zagmutt, S.; Casals, N; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2021
    Vol.: 22 No.: 12
    DOI: https://dx.doi.org/10.3390/ijms22126186 ISSN or title: 1422-0067
  • British journal of pharmacology, Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
    Name: Miralpeix, C.; Reguera, AC.; Fosch, A.; Casas, M.; Lillo, J.; Navarro, G.; Franco, R.; Casas, J.; Alexander, S.P.H.; Casals, N; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2021
    Start page: 1507 End page: 1523 Vol.: 178 No.: 7
    DOI: https://dx.doi.org/10.1111/bph.15377 ISSN or title: 0007-1188
  • Progress in lipid research, The return of malonyl-CoA to the brain: Cognition and other stories
    Name: Fadó, R.; Rodriguez-Rodriguez, R.; Casals, N Role: Autor Publishing date: 2021
    Vol.: 81
    DOI: https://dx.doi.org/10.1016/j.plipres.2020.101071 ISSN or title: 0163-7827
  • Cell metabolism, Central ceramide signaling mediates obesity-induced precocious puberty
    Name: Heras, V.; Castellano, J.M.; Fernandois, D.; Velasco, I.; Rodríguez-Vázquez, E.; Roa, J.; Vazquez, M.J.; Ruiz-Pino, F.; Rubio, M.; Pineda, R.; Torres, E.; Avendaño, M.S.; Paredes, A.H.; Pinilla, L.; Belsham, D.D.; Diéguez, C.; Gaytán, F.; Casals, N; López, M.; Tena-Sempere, M. Role: Autor Publishing date: 2020
    Start page: 951 End page: 966 Vol.: 32 No.: 6
    DOI: https://dx.doi.org/10.1016/j.cmet.2020.10.001 ISSN or title: 1550-4131
  • Journal of cell biology, Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
    Name: Casas, M.; Fadó, R.; Domínguez, J.L.; Roig, A.; Kaku, M.; Chohnan, S.; Solé, M.; Unzeta, M.; Miñano-Molina, A.; Rodríguez, J.; Dickson, E.; Casals, N Role: Autor Publishing date: 2020
    Vol.: 219 No.: 10
    DOI: https://dx.doi.org/10.1083/jcb.201912045 ISSN or title: 0021-9525
  • Faseb journal, Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD
    Name: Weber, M.; Mera, P.; Casas, J.; Salvador, J.; Rodriguez, A.; Alonso, S.; Sebastián, D.; Soler-Vázquez, M.C.; Montironi, C.; Recalde, S.; Fucho, R.; Calderón Domínguez, M.; Mir, J.; Bartrons, R.; Escolá-Gil, J.; Sánchez-Infantes, D.; Zorzano, A.; Llorente-Cortés, V.; Casals, N; Valentí, V.; Frúhbeck, G.; Herrero, L.; Serra, D. Role: Autor Publishing date: 2020
    Start page: 11816 End page: 11837 Vol.: 34 No.: 9
    DOI: https://dx.doi.org/10.1096/fj.202000678R ISSN or title: 0892-6638
  • Nanomedicine, An overview of nanomedicines for neuron targeting
    Name: Garcia-Chica, J.; Paraiso, W.; Tanabe, S.; Serra, D.; Herrero, L.; Casals, N; Garcia, J.; Ariza, X.; Quader, S.; Rodriguez-Rodriguez, R. Role: Autor Publishing date: 2020
    Start page: 1617 End page: 1636 Vol.: 15 No.: 16
    DOI: https://dx.doi.org/10.2217/nnm-2020-0088 ISSN or title: 1743-5889
  • Biochemica pharmacology, Drug uptake-based chemoresistance in breast cancer treatment
    Name: Muley, H.; Fadó, R.; Rodriguez-Rodriguez, R.; Casals, N Role: Autor Publishing date: 2020
    Vol.: 177
    DOI: https://dx.doi.org/10.1016/j.bcp.2020.113959 ISSN or title: 0006-2952
  • eNeuro, Proteasomal-Mediated Degradation of AKAP150 Accompanies AMPAR Endocytosis during cLTD
    Name: Cheng, W.; Siedlecki-Wullich, D.; Català-Solsona, J.; Fàbregas, C.; Fadó, R.; Casals, N; Solé, M.; Unzeta, M.; Saura, C.; Rodríguez, J.; Miñano-Molina, A. Role: Autor Publishing date: 2020
    Vol.: 7 No.: 2
    DOI: https://dx.doi.org/10.1523/ENEURO.0218-19.2020 ISSN or title: 2373-2822
  • eLife, Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
    Name: Palomo-Guerrero, M.; Fadó, R.; Casas, M.; Pérez-Montero, M.; Baena, M.; Helmer, PO.; Domínguez, JL.; Roig, A.; Serra, D.; Hayen, H.; Stenmark, H.; Raiborg, C.; Casals, N Role: Autor Publishing date: 2019
    Vol.: 8
    DOI: https://dx.doi.org/10.7554/eLife.51063 ISSN or title: 2050-084X
  • Biochimica et Biophysica Acta - Molecular Basis of Disease, Blood-brain barrier dysfunction underlying Alzheimer's disease is induced by an SSAO/VAP-1-dependent cerebrovascular activation with enhanced Aβ deposition
    Name: Solé, M.; Esteban, M.; Taltavull, B.; Fàbregas, C.; Fadó, R.; Casals, N; Rodríguez, J.; Miñano-Molina, A.; Unzeta, M. Role: Autor Publishing date: 2019
    Start page: 2189 End page: 2202 Vol.: 1865 No.: 9
    DOI: https://dx.doi.org/10.1016/j.bbadis.2019.04.016 ISSN or title: 1879-260X 09254439
  • Journal of lipid research, Hypothalamic endocannabinoids inversely correlate with the development of diet-induced obesity in male and female mice
    Name: Miralpeix, C.; Fosch, A.; Casas, J.; Baena, M.; Herrero, L.; Serra, D.; Rodriguez-Rodriguez, R.; Casals, N Role: Autor Publishing date: 2019
    Start page: 1260 End page: 1269 Vol.: 60 No.: 7
    DOI: https://dx.doi.org/10.1194/jlr.M092742 ISSN or title: 0022-2275
  • Molecular Metabolism, CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
    Name: Rodriguez-Rodriguez, R.; Miralpeix, C.; Fosch, A.; Pozo Ariza, M; Calderón Domínguez, M.; Perpinyà, X.; Vellvehi, M.; López, M.; Herrero, L.; Serra, D.; Casals, N Role: Autor Publishing date: 2019
    Start page: 75 End page: 85 Vol.: 19
    DOI: https://dx.doi.org/10.1016/j.molmet.2018.10.010 ISSN or title: 2212-8778
  • Frontiers in Molecular Neuroscience, Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement
    Name: Gratacós, E.; Olivella, M.; Sánchez, N.; Yefimenko, N.; Miguez, F.; Fadó, R.; Casals, N; Gasull, X.; Ambrosio, S.; Soto, D. Role: Autor Publishing date: 2018
    Vol.: 11 No.: 275
    DOI: https://dx.doi.org/10.3389/fnmol.2018.00275 ISSN or title: 1662-5099
  • Scientific Reports, CPT1C promotes human mesenchymal stem cells survival under glucose deprivation through the modulation of autophagy
    Name: Roa, X.; Al-Atari Abou-Asi, M; Fadó, R.; Mir, J.; Muley, H.; Serra, D.; Casals, N Role: Autor Publishing date: 2018
    Vol.: 8
    DOI: https://dx.doi.org/10.1038/s41598-018-25485-7 ISSN or title: 2045-2322
  • Molecular neurobiology, Ghrelin causes a decline in GABA release by reducing fatty acid oxidation in cortex
    Name: Mir, J.; Zagmutt, S.; Lichtenstein, M.; Casals, N; Herrero, L.; Serra, D. Role: Autor Publishing date: 2018
    Start page: 7216 End page: 7228 Vol.: 55
    DOI: https://dx.doi.org/10.1007/s12035-018-0921-3 ISSN or title: 0893-7648
  • Neuroscience, Uridine-5'-triphosphate partially partially blocks differentiation signals and favors a more repair state in cultured rat Schwann cells
    Name: Palomo-Guerrero, M.; Cosgaya, J.; Gella, A.; Casals, N; Grijota-Martinez,C. Role: Autor Publishing date: 2018
    DOI: https://dx.doi.org/10.1016/j.neuroscience.2018.01.010 ISSN or title: 0306-4522
  • Scientific Reports, Increased infammation, oxidative stress and mitochondrial respiration in brown adipose tissue from obese mice
    Name: Alcalá, M.; Calderón Domínguez, M.; Bustos, E.; Ramos, P.; Casals, N; Serra, D.; Viana, M.; Herrero, L. Role: Autor Publishing date: 2017
    Vol.: 7
    DOI: https://dx.doi.org/10.1038/s41598-017-16463-6 ISSN or title: 2045-2322
  • Scientific Reports, Astrocytes and oligodendrocytes in grey and white matter regions of the brain metabolize fatty acids
    Name: Hofmann, K.; Rodriguez-Rodriguez, R.; Gaebler, A.; Casals, N; Scheller, A.; Kuerschner, L. Role: Autor Publishing date: 2017
    Vol.: 7
    DOI: https://dx.doi.org/10.1038/s41598-017-11103-5 ISSN or title: 2045-2322
  • Molecular nutrition and food research, Mediterranean tomato-based sofrito protects against vascular alterations in obese Zucker rats by preserving NO bioavailability
    Name: Rodriguez-Rodriguez, R.; Jimenez-Altayo, F.; Alsina, L.; Onetti, Y.; Rinaldi de Alvarenga, J.; Claro, C.; Ogalla, E.; Casals, N; Lamuela Raventos, R. Role: Autor Publishing date: 2017
    Vol.: 61 No.: 9
    DOI: https://dx.doi.org/10.1002/mnfr.201601010 ISSN or title: 1613-4125
  • Cell metabolism, Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance
    Name: Martínez Sánchez, N.; Seoane Collazo, P.; Contreras, C.; Valera, L.; Villarroya, J.; Rial Pensado, E.; Buque, X.; Aurrekoetxea, I.; Delgado, M.; Martinez Vazquez, J.; Gonzalez, R.; Roa, J.; whittle, A.; Gomez, B.; Velagapudi, V.; Loraine, Y.; Morgan, D.; Voshol, P.; Martinez de morterin, P.; Lopez, T.; Linares Pose, L.; Gonzalez, F.; Chatterjee, K.; Sobrino, T.; Medina, G.; Davis, R.; Casals, N; Oresic, M.; Coll, A.; Vidal Puig, A.; Mittag, J.; Sempere, M.; Malagon, M.; Dieguez, C.; Martinez Chantar, M.; Espichueta, P.; Rahmouni, K.; Nogueiras, R.; Sabio, G.; Villarroya, F.; López, M. Role: Autor Publishing date: 2017
    Start page: 212 End page: 229 Vol.: 26 No.: 1
    DOI: https://dx.doi.org/10.1016/j.cmet.2017.06.014 ISSN or title: 1550-4131
  • Endocrinology, Hypothalamic regulation of liver and muscle nutrient partitioning by brain-specific carnitine palmitoyltransferase 1C (CPT1C) in male mice
    Name: Pozo Ariza, M; Rodriguez-Rodriguez, R.; Ramírez, S.; Seoane Collazo, P.; López, M.; Serra, D.; Herrero, L.; Casals, N Role: Autor Publishing date: 2017
    DOI: https://dx.doi.org/10.1210/en.2017-00151 ISSN or title: 1945-7170
  • Faseb journal, Ceramides and mitochondrial fatty acid oxidation in obesity
    Name: Fucho, R.; Casals, N; Serra, D.; Herrero, L. Role: Autor Publishing date: 2017
    Start page: 1263 End page: 1272 Vol.: 31 No.: 4
    DOI: https://dx.doi.org/10.1096/fj.201601156R ISSN or title: 0892-6638
  • Diabetes, Reduction of Hypothalamic Endoplasmic Reticulum Stress Activates Browning of White Fat and Ameliorates Obesity
    Name: Contreras, C.; Gonzalez, Mj.; Seoane-Collazo, P.; Casals, N; Diéguez, C.; Nogueiras, R.; López, M. Role: Autor Publishing date: 2017
    Vol.: 66 No.: 1
    DOI: https://dx.doi.org/10.2337/db15-1547 ISSN or title: 0012-1797
  • Journal of physiology and biochemistry, Abstracts of the XXXVIII Congress of the Spanish Society of Physiological Sciences (SECF), 13-16 September 2016, Zaragoza, Spain.
    Name: Palomo-Guerrero, M.; Fadó, R.; Moreno, B.; Rodríguez-Rodríguez, R.; Casals, N Role: Autor Publishing date: 2016
    Start page: S10 End page: S11
    ISSN or title: 1138-7548
  • Progress in lipid research, Carnitine palmitoyltransferase 1C: From cognition to cancer
    Name: Casals, N; Zammit, V.; Herrero, L.; Fadó, R.; Rodriguez-Rodriguez, R.; Serra, D. Role: Autor Publishing date: 2016
    Start page: 134 End page: 148 Vol.: 61
    ISSN or title: 0163-7827
  • Journal of biological chemistry, Novel Regulation of the Synthesis of alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus
    Name: Fadó, R.; Soto, D.; Minano-Molina, A.; Pozo Ariza, M; Carrasco, P.; Yefimenko, N.; Rodriguez-Alvarez, J.; Casals, N Role: Autor Publishing date: 2015
    Start page: 25548 End page: 25560 Vol.: 290 No.: 42
    DOI: https://dx.doi.org/10.1074/jbc.M115.681064 ISSN or title: 0021-9258
  • JAMA Neurology, Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia
    Name: Rinaldi, C.; Schmidt, T.; Situ, A.; Johnson, J.; Lee, P.; Ke-lian, C.; Bott, L.; Fadó, R.; Harmison, G.; Parodi, S.; Grunseich, C.; Renvoise, B.; Biesecker, L.; De Michele, G.; Santorelli, F.; Filla, A.; Stevanin, G.; Duerr, A.; Brice, A.; Casals, N; Traynor, B.; Blackstone, C.; Ulmer, T.; Fischbeck, K. Role: Autor Publishing date: 2015
    Start page: 561 End page: 570 Vol.: 72 No.: 5
    DOI: https://dx.doi.org/10.1001/jamaneurol.2014.4769 ISSN or title: 2168-6149
  • American journal of physiology. Endocrinology and metabolism, Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
    Name: Malandrino, M.; Fucho, R.; Weber, M.; Calderón Domínguez, M.; Mir, J.; Valcarcel, L.; Escote, X.; Gómez Serrano, M.; Peral, B.; Salvado, L.; Fernández Veledo, S.; Casals, N; Vázquez-Carrera, M.; Villarroya, F.; Vendrell, J.; Serra, D.; Herrero, L. Role: Autor Publishing date: 2015
    Vol.: 308 No.: 9
    DOI: https://dx.doi.org/10.1152/ajpendo.00362.2014 ISSN or title: 0193-1849
  • Cell Reports, Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance
    Name: Contreras, C.; González García, I.; Martínez Sánchez, N.; Seoane Collazo, P.; Jacas Mateu, J; Morgan, D.; Serra, D.; Gallego, R.; González, F.; Casals, N; Nogueiras, R.; Rahmouni, K.; Dieguez, C.; López, M. Role: Autor Publishing date: 2014
    Start page: 366 End page: 377 Vol.: 9 No.: 1
    DOI: https://dx.doi.org/10.1016/j.celrep.2014.08.057 ISSN or title: 2211-1247
  • Diabetes, Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin
    Name: Gao, S.; McMillan, R.; Jacas Mateu, J; Zhu, Q.; Li, X.; Kumar, G.; Casals, N; Hegardt, F.; Robbins, P.; Lopaschuk, G.; Hulver, M.; Butler, A. Role: Autor Publishing date: 2014
    Start page: 3242 End page: 3252 Vol.: 63 No.: 10
    DOI: https://dx.doi.org/10.2337/db14-0388 ISSN or title: 0012-1797
  • PLoS One, Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation
    Name: Lamarca, A.; Gella, A.; Martiañez, T.; Segura, M.; Figueiro, J.; Grijota-Martinez,C.; Trullas, R.; Casals, N Role: Autor Publishing date: 2014
    Vol.: 9 No.: 6
    DOI: https://dx.doi.org/10.1371/journal.pone.0098998 ISSN or title: 1932-6203
  • The journal of biological chemistry (Versió web), Defective in Mitotic Arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation.
    Name: Hernández-Ortega, S; Bru, S.; Ricco, N.; Ramírez, S.; Casals, N; Jiménez, J.; Isasa, M.; Crosas, B.; Clotet, J. Role: Autor Publishing date: 2013
    Start page: 4704 End page: 4714 Vol.: 288 No.: 7
    DOI: https://dx.doi.org/10.1074/jbc.M112.426593 ISSN or title: 1083-351X
  • Purinergic Signalling, N-cadherin expression is regulated by UTP in schwannoma cells
    Name: Martiáñez, T.; Lamarca, A.; Casals, N; Gella, A. Role: Autor Publishing date: 2013
    Start page: 259 End page: 270 Vol.: 9
    ISSN or title: 1573-9538
  • Diabetes, hypothalamic ceramide levels regulated by CPTC1C mediate the oxigenic effect of ghrelin
    Name: Ramírez, S.; Martins, L.; Jacas Mateu, J; Carrasco, P.; Pozo Ariza, M; Clotet, J.; Serra, D.; Hegardt , FG.; Diéguez, C.; López, M.; Casals, N Role: Autor Publishing date: 2013
    Start page: 2329 End page: 2337 Vol.: 62
    DOI: https://dx.doi.org/10.2337/db12-1451 ISSN or title: 0012-1797
  • Physiology and behavior, Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei
    Name: Gao, S.; Casals, N; keung, W.; Moran, TH.; Lopaschuk, GD. Role: Autor Publishing date: 2013
    Start page: 165 End page: 170 Vol.: 118
    ISSN or title: 0031-9384
  • Behavioural brain research, Carnitine palmitoyltransferase 1C deficiency causes motor impairment and hypoactivity.
    Name: Carrasco, P.; Jacas Mateu, J; Sahún, I.; Muley, H.; Ramírez, S.; Puisac , B.; Mezquita, Pau; Pié, J.; Dierssen , M.; Casals, N Role: Autor Publishing date: 2013
    Start page: 291 End page: 297 Vol.: 256
    DOI: https://dx.doi.org/10.1016/j.bbr.2013.08.004 ISSN or title: 0166-4328
  • Journal of lipid research, Characterization of a novel HMG-CoA lyase enzyme with a dual location in endoplasmic reticulum and cytosol
    Name: Arnedo, M.; Menao, S.; Puisac, B.; Teresa-Rodrigo, ME; Maria, E.; Gil-Rodríguez, M.; Maria, C.; López-Viñas, E.; Gómez-Puertas, P.; Casals, N; Casale, Cesar H.; Hegardt , FG. Role: Autor Publishing date: 2012
    Start page: 2046 End page: 2056 Vol.: 53 No.: 10
    DOI: https://dx.doi.org/10.1194/jlr.M025700 ISSN or title: 0022-2275
  • Mol Biol Rep, Characterization of splice variants of the genes encoding human mitochondrial HMG-CoA lyase and HMG-CoA synthase, the main enzymes of the ketogenesis pathway.
    Name: Puisac, B.; Ramos, M.; Arnedo, M.; Menao, S.; Gil-Rodríguez, M.; Teresa-Rodrigo, ME; Pié, A.; de Karam, JC; Wesselink, JJ; Giménez, I.; Ramos, FJ; Casals, N; Gómez-Puertas, P.; Hegardt , FG.; Pié, J. Role: Autor Publishing date: 2012
    Start page: 4777 End page: 4785 Vol.: 39
  • Journal of biological chemistry, Ceramide levels regulated by carnitine palmitoyl transferase 1C control dendritic spine maturation and cognition.
    Name: Carrasco, P.; Sahún, I.; McDonald, J.; Ramírez, S.; Jacas Mateu, J; Gratacós, E.; Sierra, AY; Serra, D.; Herrero, L.; Acker-Palmer, A.; Hegardt , FG.; Dierssen , M.; Casals, N Role: Autor Publishing date: 2012
    ISSN or title: 0021-9258
  • Journal of Cell Science, Dental Pulp of the Third Molar: A New Source of Pluripotent-like Stem Cells.
    Name: Al-Atari Abou-Asi, M; Gil-Recio, C.; Fabregat, M.; García-Fernández, DA.; Barajas, M.; Carrasco, M.; Jung, H.; Hernandez Alfaro, F; Casals, N; Prósper, F.; Ferrés, E.; Giner Tarrida, L Role: Autor Publishing date: 2012
    Start page: 3343 End page: 3356 Vol.: 125 No.: 14
    DOI: https://dx.doi.org/10.1242/jcs.096537 ISSN or title: 0021-9533
  • Neuroscience and Medicine, A Nucleotide-Based Drug Protects against Glutamate- and MPP+-Induced Neurotoxicity
    Name: Gella, A.; Martiañez, T.; Lamarca, A.; Gutierrez, C.; Durany, N.; Casals, N Role: Autor Publishing date: 2011
    Start page: 154 End page: 160 Vol.: 2
    DOI: https://dx.doi.org/10.4236/nm.2011.22022
  • American journal of physiology. Regulatory integrative and comparative physiology, Malonyl-CoA Mediates Leptin Hypothalamic Control of Feeding Independent of Inhibition of CPT-1a.
    Name: Gao, S.; keung, W.; Serra, D.; Wang, W.; Carrasco, P.; Casals, N; Hegardt , FG.; Moran, TH.; Lopaschuk, GD. Role: Autor Publishing date: 2011
    Start page: 209 End page: 217 Vol.: 301
    ISSN or title: 0363-6119
  • Histology and histopathology, Isolation of pluripotent stem cells from human third molar dental pulp
    Name: Al-Atari Abou-Asi, M; Barajas, M.; Hernandez Alfaro, F; Gil-Recio, C.; Fabregat, M.; Ferrés, E.; Giner Tarrida, L; Casals, N Role: Autor Publishing date: 2011
    Start page: 1057 End page: 1070 Vol.: 26
    DOI: https://dx.doi.org/10.14670/HH-26.1057 ISSN or title: 0213-3911
  • Proceedings of the National Academy of Sciences of the United States of America, Important Roles for Brain-specific Carnitine Palmitoyltransferase and Ceramide Metabolism in Leptin Hypothalamic Control of Feeding
    Name: Gao, S.; Zhu, G.; Gao, X.; Wu, D.; Carrasco, P.; Casals, N; keung, W.; Hegardt , FG.; Moran, TH.; Lopaschuk, GD. Role: Autor Publishing date: 2011
    Start page: 9691 End page: 9696 Vol.: 108
    ISSN or title: 0027-8424
  • Journal of inherited metabolic disease, Differential HMG-CoA lyase expression in human tissues provides clues about 3-hydroxy-3-methylglutaric aciduria
    Name: Puisac, B.; Arnedo, M.; Casale, Cesar H.; Ribate, MP; Castiella, T.; Ramos, FJ; Ribes, A.; Pérez-Cerdá, C.; Casals, N; Hegardt , FG.; Pié, J. Role: Autor Publishing date: 2010
    Start page: 405 End page: 410 Vol.: 33 No.: 4
    DOI: https://dx.doi.org/10.1007/s10545-010-9097-3 ISSN or title: 0141-8955
  • Tissue engineering. Part A, tissue engineering, Buccal fat pad, an oral access-source of human adipose stem cells with potential for osteochondral tissue engineering, an in vitro study
    Name: Ferre, E.; Martí, C.; Hernandez Alfaro, F; Klein-Nulend, J.; Casals, N Role: Autor Publishing date: 2010
    Start page: 1083 End page: 1095 Vol.: 16 No.: 5
    DOI: https://dx.doi.org/10.1089/ten.TEC.2009.0487 ISSN or title: 1937-3341
  • American Journal of Medical Genetics A, Mutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndrome.
    Name: Pié, J.; Gil-Rodríguez, M.; Ciero, M.; López-Viñas, E.; Ribate, MP; Arnedo, M.; Deardorff, M.; Puisac, B.; Legarreta, J.; de Karam, JC; Egío, E.; Bueno, I.; Baldellou, A.; Calvo, MT; Casals, N; Olivares, JL; Losada, A.; Hegardt , FG. Role: Autor Publishing date: 2010
    Start page: 924 End page: 929 Vol.: 152A
    ISSN or title: 1552-4833
  • Human mutation, Ten Novel HMGCL Mutations in 24 Patients of Different Origin with 3-Hydroxy-3-Methyl-Glutaric Aciduria
    Name: Menao, S.; López-Viñas, E.; Flores-Mir, C.; Puisac, B.; Gratacós, E.; Arnedo, M.; Carrasco, P.; Serra, D.; Asins, G.; Ramos, FJ; Gómez-Puertas, P.; Hegardt , FG.; Casals, N; Pié, J. Role: Autor Publishing date: 2009
    Start page: 520 End page: 529 Vol.: 3
    ISSN or title: 1059-7794
  • Journal of biological chemistry, CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity
    Name: Sierra, A.; Gratacós, E.; Carrasco, P.; Clotet, J.; Ureña, J.; Serra, D.; Asins, G.; Hegardt, F.; Casals, N Role: Autor Publishing date: 2008
    Start page: 6878 End page: 6885 Vol.: 283 No.: 11
    DOI: https://dx.doi.org/10.1074/jbc.M707965200 ISSN or title: 0021-9258
  • Analytica chimica acta, A new lc-esi-ms/ms method to measure acylcarnitine levels in cultured cells
    Name: Casals, N Role: Autor Publishing date: 2007
    Start page: 1 End page: 6 Vol.: 599
    ISSN or title: 0003-2670
  • Molecular genetics and metabolism, Molecular genetics of HMG-CoA lyase deficiency
    Name: Casals, N Role: Autor Publishing date: 2007
    Start page: 198 End page: 209 Vol.: 92
    ISSN or title: 1096-7192
  • Molecular genetics and metabolism, C-Terminal end amd aminoacid Lys48in HMG-CoA lyase are involved in substrate binding and enzyme activity.
    Name: Casals, N Role: Autor Publishing date: 2007
    Start page: 120 End page: 127 Vol.: 91
    ISSN or title: 1096-7192
  • Journal of inherited metabolic disease, Refining the diagnosis of mitochondrial HMG-CoA synthase deficiency
    Name: Casals, N Role: Autor Publishing date: 2006
    Start page: 207 End page: 211 Vol.: 29
    ISSN or title: 0141-8955
  • Journal of inherited metabolic disease, A single residue mutation, G203E, causes 3-hydroxy-3-methylglutaric aciduria by occluding the substrate channel in the 3D structural model of HMG-CoA lyase
    Name: Casals, N Role: Autor Publishing date: 2006
    Start page: 64 End page: 70 Vol.: 29
    ISSN or title: 0141-8955
  • Biophysical chemistry, Skipping of exon 2 and exon 2 plus 3 of HMG-CoA lyase (HL) gene produce the loss of beta sheet 1 and 2 at the recently proposed (beta-alfa)8 TIM barrel model of HL.
    Name: Casals, N Role: Autor Publishing date: 2005
    Start page: 241 End page: 245 Vol.: 115
    ISSN or title: 0301-4622
  • Journal of biological chemistry, Structural (beta alpha)(8) TIM barrel model of 3-hydroxy-3-methylglutaryl-coenzyme A lyase
    Name: Casals, N; Gómez-Puertas, P.; Pié, J.; Mir, C.; Roca, R.; Puisac, B.; Aledo, R.; Clotet, J.; Menao, S.; Serra, D.; Asins, G.; Till, J.; Alun, C.; Jones, E.; Cresto, Juan C.; Chamoles, Nestor A; Abdenur, Jose E; Mayatepek, E.; Besley, G.; Valencia, A.; Hegardt , FG. Role: Autor Publishing date: 2003
    Start page: 29016 End page: 29023 Vol.: 278 No.: 31
    DOI: https://dx.doi.org/10.1074/jbc.M304276200 ISSN or title: 0021-9258
  • Journal of physiology and biochemistry, Molecular basis of 3-hydroxy 3-methylglutaric aciduria
    Name: Casals, N Role: Autor Publishing date: 2003
    Start page: 311 End page: 322 Vol.: 59
    ISSN or title: 1138-7548
  • Journal of biological chemistry, Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition
    Name: Morillas, M.; Bentebibel, A.; Selles, E.; Casals, N; Valencia, A.; Hegardt , FG.; Asins, G.; Serra, D.; Gómez-Puertas, P. Role: Autor Publishing date: 2003
    Start page: 9058 End page: 9063 Vol.: 278
    ISSN or title: 0021-9258
  • Yeast, Identification of multicopy supressors of cell cycle arrest at the G1-S transition in Saccharomyces cerevisiae.
    Name: Muñoz, I.; Simón, E.; Casals, N; Clotet, J.; Ariño, J. Role: Autor Publishing date: 2003
    Start page: 157 End page: 169 Vol.: 30
    ISSN or title: 0749-503X
  • Journal of molecular neuroscience, CDP-choline prevents glutamate-mediated cell death in cerebellar granule neurons
    Name: Mir, C.; Clotet, J.; Aledo, R.; Durany, N.; Argemí Renom, J; Lozano, R.; Cervós-Navarro, J.; Casals, N Role: Autor Publishing date: 2003
    Start page: 53 End page: 59 Vol.: 20
    ISSN or title: 0895-8696
  • Journal of pediatrics, Diagnosing mitochondrial HMG-CoA synthase deficiency
    Name: Casals, N Role: Autor Publishing date: 2002
    Start page: 778 End page: 780 Vol.: 140
    ISSN or title: 0022-3476
  • Human genetics, The genetic basis of mitochondrial HMG-CoA synthase deficiency
    Name: Casals, N Role: Autor Publishing date: 2001
    Start page: 19 End page: 23 Vol.: 109
    ISSN or title: 0340-6717
  • Insect molecular biology, 3-hydroxy-3-methylglutaryl CoA synthase-1 of Blattella germanica has structural and functional features of an active retrogene
    Name: Casals, N Role: Autor Publishing date: 2001
    Start page: 837 End page: 743 Vol.: 31
    ISSN or title: 0962-1075
  • Archives of biochemistry and biophysics, A nonsense mutation in the exon 2 of the 3-hydroxy-3-methylglutaryl CoA lyase (HL) gene producing three mature mRNAs is the main cause of 3-hydroxy-3-methylglutaric aciduria in european mediterranean patients
    Name: Casals, N Role: Autor Publishing date: 1998
    Vol.: 349
    ISSN or title: 0003-9861
  • Archives of biochemistry and biophysics, Two missense point mutations in different alleles in the 3-hydroxy-3-methylglutaryl Coenzyme A Lyase gene produce 3-hydroxy-3methylglutaric aciduria in a french patient
    Name: Casals, N Role: Autor Publishing date: 1998
    Start page: 197 End page: 203 Vol.: 358
    ISSN or title: 0003-9861
  • Journal of lipid research, A two-base deletion in exon 6 of the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene producing the skipping of exons 5 and 6 determines 3-hydroxy-3-methylglutaric aciduria
    Name: Casals, N Role: Autor Publishing date: 1997
    Start page: 90 End page: 100 Vol.: 38
    ISSN or title: 0022-2275
  • Biochemica journal, A nonsense mutation in the 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene produces exon-skipping in two patiens of different origin with hl deficiency
    Name: Casals, N Role: Autor Publishing date: 1997
    Start page: 329 End page: 335 Vol.: 323
    ISSN or title: 0264-6021
  • Physiological entomology, Expression and activity of 3-hydroxy-3-methylglutaryl-CoA synthase and reductase in the fat body of ovariectomized and allatectomized Blattella germanica
    Name: Casals, N Role: Autor Publishing date: 1997
    Start page: 6 End page: 12 Vol.: 22
    ISSN or title: 0307-6962
  • Gaceta sanitaria, La prescripción farmacéutica en Catalunya tras el decreto de financiación selectiva de medicamentos
    Name: Casals, N Role: Autor Publishing date: 1996
    Start page: 183 End page: 190 Vol.: 10
    ISSN or title: 0213-9111
  • Insect molecular biology, Coordinated Expression and Activity of 3-hydroxy-3-methylglutaryl CoA synthase and reductase in the fat body of Blattella germanica during vitellogenesis
    Name: Casals, N Role: Autor Publishing date: 1996
    Start page: 837 End page: 843 Vol.: 26
    ISSN or title: 0962-1075
  • Journal of lipid research, An aberrant splicing by a point mutation and a deletion in 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL) gene produce an hereditary hl deficiency
    Name: Casals, N Role: Autor Publishing date: 1996
    Start page: 2420 End page: 2431 Vol.: 37
    ISSN or title: 0022-2275
  • Journal of biological chemistry, Blattella germanica Has Two HMG-CoA Synthase Genes. Both Are Regulated In The Ovarian Development
    Name: Casals, N Role: Autor Publishing date: 1994
    Start page: 11707 End page: 11713 Vol.: 269
    ISSN or title: 0021-9258
  • Archives of biochemistry and biophysics, Regulation of Mitochondrial 3-Hydroxy-3-Methylglutaryl-coenzime A Synthase Protein by Starvation, Fat Feeding and Diabetes
    Name: Casals, N Role: Autor Publishing date: 1993
    Start page: 40 End page: 45 Vol.: 307
    ISSN or title: 0003-9861
  • Biochemica journal, Regulation of the expression of the mitochondrial 3-hidroxy-3-methylglutaryl-CoA synthase gene
    Name: Casals, N Role: Autor Publishing date: 1992
    Vol.: 283
    ISSN or title: 0264-6021
  • El DNA es pot manipular.
    Publishing date: 2008

Patents

  • PLURIPOTENT STEM CELLS OBTAINED FROM DENTAL PULP
    Owner: Al-Atari Abou-Asi, M; Casals, N; Giner Tarrida, L; Ferrés, E.
    Property type: Altres Application number: DSM ACC3002 Application date: 21/07/2010
    Description: Pais prioritat: España Paisos: Europa y Estados Unidos (US 9.017.663 B2) date: 28/04/2015
  • Células madre pluripotenciales obtenidas a partir de la pulpa dental
    Owner: Al-Atari Abou-Asi, M; Casals, N; Ferrés, E.; Giner Tarrida, L
    Property type: Altres Application number: P200930488 Application date: 21/07/2009
    Description: REGENERAR TEJIDO OSEO. LA PRESENTE INVENCION SE REFIERE A LAS CELULAS MADRE PLURIPOTENTES OBTENIDAS A PARTIR DE LA PULPA DENTAL DE PACIENTES DE DIFERENTES EDADES, LA INVENCION COMPRENDE ADEMAS CULTIVOS DE DICHAS CELULAS, LOS MEDIOS PARA SU OBTENCION Y COMPOSICIONES FARMACEUTICAS QUE LOS COMPRENDEN, ASI COMO SU APLICACION EN LA REGENERACION DE LOS TEJIDOS.
  • Células madre mesenquimales, procedimiento de obtención y uso de estas
    Owner: Casals, N; Martí, C.; Farré, E.
    Property type: Altres Application number: P 200803111 Application date: 01/01/1900
    Description: Pais prioritat: Espanya
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Humanities and Cultural Studies
    • - Theory of Knowledge
    Bachelor's Degree in Nursing
    • - Surgical and Critical Care Nursing
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Biomedical Sciences
    • - Pharmacology
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Surgical and Critical Care Nursing
  • Official Master
    Master's Degree in Research in Dentistry
    • - Basic Pharmacology
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Surgical and Critical Care Nursing
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    • - Pharmacology
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
  • Others
    Programa Gaudí de Formació del Professorat 18 - 19
    • - Mòdul 3 Recerca i Innovació
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
    Bachelor's Degree in Nursing
    • - Advanced Clinical Pathology
  • Official Master
    Master's Degree in Research in Dentistry
    • - Pre-Clinical and Clinical Pharmacology
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
  • Official Master
    Master's Degree in Research in Dentistry
    • - Farmacologia Preclínica y Clínica
    • - Pre-Clinical and Clinical Pharmacology
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
  • Official Master
    Master's Degree in Research in Dentistry
    • - Pre-Clinical and Clinical Pharmacology
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Body Structure and Function: Gastrointestinal System and Metabolism
Course 2012-2013 - Period: 01/09/2012 - 31/08/2013
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
    • - Regenerative Medicine and Use of Haematopoietic Progenitor Cells
  • Official Master
    University Master's degree in Basic Dentistry Research and Biomedicine
    • - Actualitat de la Recerca en Odontologia
    • - Bioinformatics
    • - Final Master's Project
Course 2011-2012 - Period: 01/09/2011 - 31/08/2012
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Cellular Therapy and Regenerative Medicine. Bone Marrow, Organ and Tissue Transplant
    • - Pharmacology
    • - Regenerative Medicine: Drug Therapy in Organ Transplants
  • Official Master
    University Master's Degree in Basic Dentistry Research and Biomedicine
    • - Bioinformatics
    • - Current Dentistry Research
    • - Final Master's Project
    • - Research Protocol
    • - Molecular and Cell Biology Techniques
Course 2010-2011 - Period: 01/09/2010 - 31/08/2011
  • Bachelor’s Degree
    Bachelor's Degree in Dentistry
    • - Pharmacology
    Bachelor's Degree in Medicine
    • - Pharmacology
  • Official Master
    University Master's Degree in Basic Dentistry Research and Biomedicine
    • - Informatic Tools for Biomedicine
    • - Actualitat de la Recerca en Odontologia
    • - Final Master's Degree Project
    • - Protocol de Recerca
Course 2009-2010 - Period: 01/09/2009 - 31/08/2010
  • Official Master
    University Master's Degree in Basic Dentistry Research and Biomedicine
    • - Patologia Mol·lecular
    • - Protocol de Recerca
  • Degree
    Degree in Dentistry
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 2008-2009 - Period: 01/09/2008 - 31/08/2009
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
  • Official Master
    University Master's degree in Basic Dentistry Research and Biomedicine
    • - Proyecto de Investigación 3
    • - Actualidad de la Investigación en Odontología
    • - Informatic Tools for Biomedicine
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 2007-2008 - Period: 01/09/2007 - 31/08/2008
  • Official Master
    University Master's degree in Basic Dentistry Research and Biomedicine
    • - Proyecto de Investigación 1
    • - Técnicas Avanzadas en Biología Molecular, Celular y Microscopía
  • Degree
    Degree in Dentistry
    • - Pharmacology
Course 2006-2007 - Period: 01/09/2006 - 31/08/2007
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Prácticas de Laboratorio de Investigación Biomédica
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 2005-2006 - Period: 01/09/2005 - 31/08/2006
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Microbiology
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Nutrition and Dietetics
    • - Pharmacology
Course 2004-2005 - Period: 01/09/2004 - 31/08/2005
  • PhD
    Doctorado para Profesionales en Atención Primaria
    • - Bases moleculares del diagnóstico precoz
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Prácticas de Laboratorio de Investigación Biomédica
    • - Microbiology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - Nutrition and Dietetics
    • - Pharmacology
Course 2003-2004 - Period: 01/09/2003 - 31/08/2004
  • PhD
    Doctorado para Profesionales en Atención Primaria
    • - Bases moleculares del diagnóstico precoz
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Microbiology
    • - Prácticas de Laboratorio de Investigación Biomédica
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Nutrition and Dietetics
    • - Pharmacology
Course 2002-2003 - Period: 01/09/2002 - 31/08/2003
  • PhD
    Doctorado para Profesionales en Atención Primaria
    • - Bases moleculares del diagnóstico precoz
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Pharmacology
    • - Microbiology
    • - Prácticas de Laboratorio de Investigación Biomédica
  • Diploma
    Diploma in Nursing
    • - Pharmacology
    • - Nutrition and Dietetics
Course 2001-2002 - Period: 01/09/2001 - 31/08/2002
  • PhD
    Doctorado para Profesionales de Atención Primaria
    • - Bases moleculares del diagnóstico y la prevención de la enfermedad
  • Degree
    Degree in Dentistry
    • - Advanced Molecular Biology
    • - Pharmacology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
  • Others
    Introduction Course in Health Sciences
    • - Biology 1
Course 2000-2001 - Period: 01/09/2000 - 31/08/2001
  • PhD
    Doctorado para Profesionales de Atención Primaria
    • - Bases moleculares del diagnóstico y la prevención de la enfermedad
  • Degree
    Degree in Dentistry
    • - Pharmacology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - Pharmacology
Course 1999-2000 - Period: 01/09/1999 - 31/08/2000
  • Degree
    Degree in Dentistry
    • - Molecular and Cell Biology
    • - Advanced Cell Biology
    • - Advanced Molecular Biology
Course 1998-1999 - Period: 01/09/1998 - 31/08/1999
  • Degree
    Degree in Dentistry
    • - Molecular and Cell Biology
    • - Advanced Cell Biology
    • - Advanced Molecular Biology
  • Diploma
    Diploma in Nursing
    • - The Human Body 1
    • - The Normal Functions of the Human Body
Course 1997-1998 - Period: 01/09/1997 - 31/08/1998
  • Degree
    Degree in Dentistry
    • - Advanced Cell Biology
    • - Molecular and Cell Biology
    • - Advanced Molecular Biology
  • Others
    Complementary Formation in Dentistry
    • - Biología Molecular y Celular
    Introduction Course in Health Sciences
    • - Metodología Científica Aplicada a la Biología 1
    • - Metodología Científica Aplicada a la Biología 2
    • - Biología Celular y Molecular 1