Directorio

SAPERAS FRANCH, Esteban

Departamento de Medicina
ORCID
ORCID
Sección

SAPERAS FRANCH, Esteban

CV

Perfil del profesor

Medicina, Facultad de Medicina y Ciencias de la Salud. Hospital General de Catalunya

Formación académica
  • Medicina y Cirugía Universidad de Barcelona
  • Licenciado en Medicina y Cirugía Universidad de Barcelona
  • Especialista en Aparato Digestivo Universidad de Barcelona
  • Doctor en Medicina y Cirugía

Publicaciones

Artículos
  • Mego, M.; Huaman, J.; Videla, S.; Jansana, M.; Tinoco, K.; Saperas, E., (2023), "Effectiveness of a high fiber diet in improving constipation in patients with defecatory dyssynergy under treatment with anorrectal biofeedback. Exploratory, randomized clinical trial Eficacia de la dieta alta en fibra en la mejora del estreñimiento en pacientes con disinergia defecatoria en tratamiento con biofeedback anorrectal. Ensayo clínico exploratorio, aleatorizado", Gastroenterologia y Hepatologia, ISSN: 0210-5705.
  • Sánchez, A.; Roos, V.H.; Navarro, M.Y.; Pineda, M.; Caballol, B.; Moreno, L.; Carballal, S.; Rodríguez Alonso, L.; Ramon y Cajal, T.; Llort, G.; Piñol, V.; López, A.; Salces, I.; Picó, M.; Rivas, L.; Bujanda, L.; Garzon, M.; Pizarro, A.; Martinez, E.; López, M.; Poves, C.; Garau, C.; Rodriguez, D.; Herraiz, M.; Alvarez, C.; Dacal, A.; Carrillo, M.; Cid, L.; Ponce, M.; Barreiro, E.; Saperas, E.; Aguirre, E.; Romero, C.; Bastiaansen, B.; Gonzalez, M.; Morales, B.; Ocaña, T.; Rivero, L.; Jung, G.; Bessa, X.; Cubiella, J.; Jover, R.; Rodríguez, F.; Balmaña, J.; Brunet, J.; Castells, A.; Dekker, E.; Capella, G.; Serra, M.; Moreira, L.; Pellise, M.; Balaguer, F., (2022), "Quality of Colonoscopy Is Associated With Adenoma Detection and Postcolonoscopy Colorectal Cancer Prevention in Lynch Syndrome", Clinical gastroenterology and hepatology, vol. 20, No. 3, pp. 611-621, ISSN: 1542-3565.
  • Cuatrecasas, M.; Gorostiaga, I.; Riera, C.; Saperas, E.; Llort, G.; Costa, I.; Matías-Guíu, X.; Carrato, C.; Navarro, M.Y.; Pineda, M.; Dueñas, N.; Brunet, J.; Marco, V.; Trías, I.; Busteros, J.I.; Mateu, G.; Balaguer, F.; Mt Fernandez-Figueras; Esteller, M.; Musulén, E., (2020), "Complete loss of epcam immunoexpression identifies epcam deletion carriers in msh2negative colorectal neoplasia", CANCERS, vol. 12, No. 10, pp. 1-20, ISSN: 2072-6694.
  • Huaman, JW; Mego, M.; Bendezú, Á.; Monrroy, H.; Samino, S.; Accarino, A.; Saperas, E.; Azpiroz, F., (2019), "Correction of Dyssynergic Defecation, but Not Fiber Supplementation, Reduces Symptoms of Functional Dyspepsia in Patients With Constipation in a Randomized Trial", Clinical gastroenterology and hepatology, ISSN: 1542-3565.
  • Huaman, JW; Mego, M.; Manichanh, C.; Cañellas, N.; Cañueto, D.; Segurola, H.; Jansana, M.; Malagelada, C.; Accarino, A.; Vulevic, J.; Tzortzis, G.; Gibson, G.; Saperas, E.; Guarner, F.; Azpiroz, F., (2018), "Effects of Prebiotics vs a Diet Low in FODMAPs in Patients With Functional Gut Disorders", Gastroenterology, vol. 155, No. 4, pp. 1004-1007, ISSN: 0016-5085.
  • Saperas, E., (2018), "Clinical guidelines for endoscopic mucosal resection of non-pedunculated colorectal lesions", Revista española de enfermedades digestivas, No. 110, pp. 179-194, ISSN: 1130-0108.
  • Saperas, E., (2016), "Enhanced flat adenoma detection rate with high definition colonoscopy plus i-scan for average-risk colorectal cancer screening", Revista española de enfermedades digestivas, vol. 108, pp. 257-262, ISSN: 1130-0108.
  • Saperas, E., (2016), "A Scoring System to Determine Risk of Delayed Bleeding after Endoscopic Mucosal Resection of Large Colorectal Lesions", Clinical gastroenterology and hepatology, vol. 14, pp. 1140-1147, ISSN: 1542-3565.
  • Del Molino Sanz, F.; Gonzalez, I.; Saperas, E., (2015), "Management of new oral anticoagulants in gastrointestinal bleeding and endoscopy", Gastroenterologia y Hepatologia, vol. 38, No. 8, pp. 501-510, ISSN: 0210-5705.
  • Huaman, JW; Felip, A.; Guedea, E.; Jansana, M.; Videla, S.; Saperas, E., (2015), "The diet low in fermentable carbohydrates short chain and polyols improves sumptoms in patients with functional gastrointestinal disorders in Spain", Gastroenterologia y Hepatologia, vol. 38, No. 2, pp. 113-122, ISSN: 0210-5705.
  • Huaman, JW; Guedea, E.; Jansana, M.; Videla, S.; Saperas, E., (2015), "The diet low in fermentable carbohydrates short chain and polyols improves simptoms in patients with functional gastrointestinal disorders in Spain", Gastroenterologia y Hepatologia, vol. 38, pp. 113-122, ISSN: 0210-5705.
  • Huaman, JW; Felip, A.; Guedea, E.; Videla, S.; Saperas, E., (2015), "The diet low in fermentable carbohydrates short chain and po lyols improves sumptoms in patients with functional gastrointestinal disorders in Spain. Gastroenterol He", Gastroenterology and hepatology, vol. 38, pp. 113-122, ISSN: 1554-7914.
  • Del Molino Sanz, F.; Gonzalez, I.; Saperas, E., (2015), "Management of new oral anticoagulants in gastrointestinal bleeding and endoscopy", Gastroenterology and hepatology, ISSN: 1554-7914.
  • Rodriguez-D´Jesus, A.; Gordillo, J.; Uchima, H.; Araujo, I.; Saperas, E.; Elizalde, I.; Fernandez-Esparrach, G., (2014), "Prevalence and epidemiology of Barrett’s esophagus in the province of Barcelona", Gastroenterologia y Hepatologia, vol. 37, pp. 397-401, ISSN: 0210-5705.
  • Huaman, JW; Aliaga, V.; Domenech, G.; Videla, S.; Saperas, E., (2014), "What is the utility of proton pump inhibitor testing in non-cardiac chest pain?", Eur J Gastroenterol Hepatol, vol. 37- Q4, pp. 452-461.
  • Rodriguez-D´Jesus, A.; Gordillo, J.; Uchima, H.; Araujo, I.; Saperas, E., (2014), "Prevalence and epidemiology of Barrett’s esophagus in the province of Barcelona", Eur J Gastroenterol Hepatol, vol. 37 -Q4, pp. 397-401.
  • Huaman, JW; Aliaga, V.; Domenech, G.; Videla, S.; Saperas, E., (2014), "What is the utility of proton pump inhibitor testing in non -­‐ cardiac chest pa", Gastroenterologia y Hepatologia, ISSN: 0210-5705.
  • Saperas, E., (2013), "Hemorragia digestiva Alta", GI Magazine, vol. 6, pp. 6-8.
  • Vicario Juan, M; Alonso, C.; Guilarte, M.; Serra, J.; Martinez, C.; Gonzalez-Castro, Am.; Lobo, B.; Antolin, M.; Andreu, Al.; Garcia-Arumi, E.; Casellas, M.; Saperas, E.; Malagelada, JR.; Azpiroz, F.; Santos, J., (2012), "Chronic psychosocial stress induces reversible mitochondrial damage and corticotropin-­‐releasing factor receptor type-­‐1 upregulation in the rat intestine and IBS-­‐like gut dysfunction", Psychoneuroendocrinology, vol. 37, pp. 65-77, ISSN: 0306-4530.
  • Martinez, C.; Vicario Juan, M; Ramos, L.; Lobo, B.; Mosquera, Jl.; Alonso, C.; Guilarte, M.; Antolin, M.; de Torres, I.; Gonzalez-Castro, Am.; Pigrau, M.; Saperas, E.; Azpiroz, F.; Santos, J., (2012), "The jejunum of diarrea-­‐predominant irritable bowel síndrome shows molecular alterations in the tight junction signaling pathway that are associated with mucosal pathobiology and clinical manifestations", American journal of gastroenterology, vol. 107, pp. 736-746, ISSN: 0002-9270.
  • Rodriguez-D´Jesus, A.; Cordova, H.; Elizalde, I.; Cuatrecasas, M.; Saperas, E.; Llach, J.; Fernandez-Esparrach, G., (2012), "Usefulnes of endoscopic biopsy in Barrett’s esophagus", Medicina clínica, vol. 13, pp. 103-106, ISSN: 0025-7753.
  • Rodriguez-D´Jesus, A.; Fernandez-Esparrach, G.; Saperas, E., (2011), "Endoscopic treatment of pancreatic pseudocyst. Practical features", Gastroenterologia y Hepatologia, vol. 34, No. 10, pp. 711-716, ISSN: 0210-5705.
  • Cerezo, Fj.; Tatros, Gm.; Mombiela, Fv.; Tomas, A.; Abad, A.; Campo, R.; Salo, J.; Boadas, J.; Baños, F.; Rigau, J.; Sabat, M.; Fabregas, S.; Vidal, L.; Planella, M.; Castellvi, J.; Gine, J.; Saperas, E.; Torra, S.; Creix, A.; Torres, M.; Rey, J.; Garcia, V.; Laguna, J.; Pascual, D.; Manso, C., (2011), "Emergency care of patients with upper gastrointestinal bleeding in regional hospitals in Catalonia", Gastroenterologia y Hepatologia, vol. 34, No. 9, pp. 605-610, ISSN: 0210-5705.
  • Vicario, M.; Guilarte, M.; Alonso, C.; Yang, P.; Martinez, C.; Ramos, L.; Lobo, B.; Gonzalez, A.; Guilà, M.; Pigrau, M.; Saperas, E.; Azpiroz, F.; Santos, J., (2010), "Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress", Brain behavior and immunity, vol. 24, pp. 1166-1175, ISSN: 0889-1591.
  • Saperas, E.; Videla, S.; Dot, J.; Bayarri, C.; Abu-Suboh, M.; Armengol, J.; Malagelada, JR., (2009), "Risk factors for recurrence of acute gastrointestinal bleeding from angiodysplasia", European journal of gastroenterology and hepatology, vol. 21, pp. 1333-1339, ISSN: 0954-691X.
  • Rezzi, S.; Martin, F.; Alonso, C.; Guilarte, M.; Vicario, M.; Ramos, L.; Martinez, C.; Lobo, B.; Saperas, E.; Malagelada, JR.; Santos, J.; Kochhar, S., (2009), "Metabotyping of biofluids reveals stress -­‐ based differences in gut permeability in healthy individuals", Journal of proteome research, vol. 8, pp. 4799-4809, ISSN: 1535-3893.
  • Augustin, S.; Muntaner, L.; Altamirano, J.; Gonzalez, A.; Saperas, E.; Dot, J.; Abu-Suboh, M.; Armengol, J.; Malagelada, JR.; Esteban, R.; Guardia, J.; Genescà, J., (2009), "Predicting early mortality after acute variceal hemorrhage based on classification and regression tree analysis", Clinical gastroenterology and hepatology, vol. 7, pp. 1347-1354, ISSN: 1542-3565.
  • Alonso, C.; Guilarte, M.; Vicario, M.; Ramos, L.; Ramadan, Z.; Antolin, M.; Martinez, C.; Rezzi, S.; Saperas, E.; Kochhar, S.; Santos, J.; Malagelada, JR., (2008), "Maladaptive intestinal epithelial responses to life stress may predispose healthy women to gut mucosal inflammation", Gastroenterology, vol. 135, pp. 163-172, ISSN: 0016-5085.
  • Guilarte, M.; Santos, J.; de Torres, I.; Alonso, C.; Vicario, M.; Ramos, L.; Martinez, C.; Saperas, E.; Malagelada, JR., (2007), "Diarrhoea -­‐ predominant IBS patients show mast cell activation and hyperplasia in the jejunum", Gut, vol. 56, pp. 203-209, ISSN: 0017-5749.
  • Saperas, E., (2007), "HDB: esa gran desconocida", Gastroenterologia y Hepatologia, vol. 30, pp. 93-100, ISSN: 0210-5705.
  • Junquera, F.; Saperas, E.; Videla, S.; Feu, F.; Vilaseca, J.; Armengol, J.; Bordas, Jm.; Pique, Jm.; Malagelada, JR., (2007), "Long -­‐ Term Efficacy of Octreotide in the Prevention of Recurrent Bleeding from Gastr ointestinal Angiodysplasia", American journal of gastroenterology, vol. 102, pp. 254-260, ISSN: 0002-9270.
  • Saperas, E.; Dot, J.; Videla, S., (2007), "Capsule endoscopy versus computed tomographic or standard angiography for the diagnosis of obscure gastrointestinal bleeding", American journal of gastroenterology, vol. 102, pp. 1-7, ISSN: 0002-9270.
  • Gonzalez, A.; Augustin, S.; Perez, M.; Dot, J.; Saperas, E., (2006), "Hemodynamic response-guided therapy for prevention of variceal rebleeding: an uncontrolled pilot study", Hepatology, vol. 44, pp. 806-812, ISSN: 0270-9139.
  • Junquera, F.; Saperas, E.; Angles, A.; Abadia, C.; Monasterio, J.; Malagelada, JR., (2005), "Increased plasma fibrinolytic activity in bleeding gastrointestinal angiodysplasia", European journal of gastroenterology and hepatology, vol. 17, pp. 199-205, ISSN: 0954-691X.
  • Lanas, A.; Perez-Aisa, Ma.; Feu, F.; Ponce, J.; Saperas, E.; Santolaria, S.; Rodrigo, L.; Balanzo, J.; Bajador, E.; Almela, P.; Navarro, Jm.; Carballo, F.; Castro, M.; Quintero, E., (2005), "A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with non-­‐steroidal anti-­‐ inflammatory drug use", American journal of gastroenterology, vol. 100, pp. 1-9, ISSN: 0002-9270.
  • Alvarez-Uria, G.; Pallero, M.; de Torres, I.; Majo, J.; Ordi, J.; Saperas, E., (2003), "Massive hemorrhage due to nodular hyperplasia of Brunner's glands in antiphospholipid syndrome", Gastroenterologia y Hepatologia, vol. 26, pp. 635-638, ISSN: 0210-5705.
  • Saperas, E., (2003), "¿ Que sabemos realmente de la angiodisplasia de colon ?", Medicina clínica, vol. 121, pp. 137-138, ISSN: 0025-7753.
  • Feu, F.; Brullet, E.; Calvet, X.; Fernandez-Llamazares, J.; Guardiola, J.; Moreno, P.; Panades, A.; Salo, J.; Saperas, E.; Villanueva, C.; Planas, R., (2003), "Guidelines for the diagnosis and treatment of acute non-­‐variceal upper gastrointestinal bleeding", Gastroenterologia y Hepatologia, vol. 26, pp. 70-85, ISSN: 0210-5705.
  • Kresse, Ae.; Million, M.; Saperas, E.; Tache, Y., (2001), "Colitis induces CRF expresión in hypothalamic magnocellular neurons and blunts CRF gene response to stress in rats", American journal of physiology. Gastrointestinal and liver physiology, vol. 281, pp. G1203-G1213, ISSN: 0193-1857.
  • Junquera, F.; Feu, F.; Papo, M.; Videla, S.; Armengol, J.; Bordas, Jm.; Saperas, E.; Pique, Jm.; Malagelada, JR., (2001), "A multicenter, randomized, controlled, clinical trial of hormonal therapy in the prevention of rebleeding from gastrointestinal angiodysplasia", Gastroenterology, vol. 121, pp. 1073-1079, ISSN: 0016-5085.
  • Vergara, M.; Casellas, F.; Saperas, E.; de Torres, I.; Lopez, J.; Borruel, N.; Armengol, J.; Malagelada, JR., (2000), "Helicobacter pylori eradication prevents recurrence from peptic ulcer haemorrhage", European journal of gastroenterology and hepatology, vol. 12, pp. 733-737, ISSN: 0954-691X.
  • Junquera, F.; Quiroga, S.; Saperas, E.; Perez-Lafuente, M.; Videla, S.; Alvarez-Castells, A.; Armengol, J.; Malagelada, JR., (2000), "Accuracy of helical computed tomographic angiography for the diagnosis of colonic angiodysplasia", Gastroenterology, vol. 119, pp. 293-299, ISSN: 0016-5085.
  • Junquera, F.; Lopez-Talavera, Jc.; Mearin, F.; Saperas, E.; Videla, S.; Armengol, J.; Esteban, R.; Malagelada, JR., (2000), "Somatostatin plus isosorbide 5-­‐mononitrate versus somatostatin in the control of acute gastro-­‐oesophageal variceal bleeding: a double blind, randomised, placebo controlled clinical trial", Gut, vol. 46, pp. 127-132, ISSN: 0017-5749.
  • Santos, J.; Bayarri, C.; Saperas, E.; Nogueiras, C.; Antolin, M.; Mourelle, M.; Cadahia, A.; Malagelada, JR., (1999), "Characterisation of immune mediator release during the immediate response to segmental mucosal challenge in the jejunum of patients with food allergy", Gut, vol. 45, pp. 553-558, ISSN: 0017-5749.
  • Junquera, F.; Saperas, E.; de Torres, I.; Vidal, Mt.; Malagelada, JR., (1999), "Increased expression of angiogenic factors in human colonic angiodysplasia", American journal of gastroenterology, vol. 94, pp. 1070-1076, ISSN: 0002-9270.
  • Casadevall, M.; Saperas, E.; Panes, J.; Salas, A.; Anderson, Dc.; Malagelada, JR.; Pique, Jm., (1999), "Mechanisms underlying the anti-­‐inflammatory actions of central corticotropin-­‐releasing factor", American journal of physiology. Gastrointestinal and liver physiology, vol. 276, pp. G1016-G1026, ISSN: 0193-1857.
  • Casellas, F.; Lopez, J.; Borruel, N.; Saperas, E.; Vergara, M.; de Torres, I.; Armengol, J.; Malagelada, JR., (1999), "The impact of delaying gastric emptying by either meal substrate or drug on the [13C]-­‐urea breath test", American journal of gastroenterology, vol. 94, pp. 369-373, ISSN: 0002-9270.
  • Martinez-Sanchez, G.; Saperas, E.; Benavent-Areu, J.; Mearin, F.; Pinol, Jl.; Barenys, M.; Marcort, Jj; Forne, M.; Bordas, Jm.; Azagra, R.; Pique, Jm., (1998), "The attitude of primary health care physicians in the metropolitan area of Barcelona about the diagnosis and treatment of Helicobacter pylori infection in gastroduodenal diseases", Gastroenterologia y Hepatologia, vol. 21, pp. 473-478, ISSN: 0210-5705.
  • Santos, J.; Saperas, E.; Nogueiras, C.; Mourelle, M.; Antolin, M.; Cadahia, A.; Malagelada, JR., (1998), "Release of mast cell mediators into the jejunum by cold pain stress in humans", Gastroenterology, vol. 114, pp. 640-648, ISSN: 0016-5085.
  • Santos, J.; Saperas, E.; Mourelle, M.; Antolin, M.; Malagelada, JR., (1996), "Regulation of intestinal mast cells and luminal protein release by cerebral thyrotropin-­‐ releasing hormone in rats", Gastroenterology, vol. 11, pp. 1465-1473, ISSN: 0016-5085.
  • Saperas, E., (1996), "The role of mast cells in gastrointestinal inflammation", Gastroenterology, vol. 110, pp. 1656-1658, ISSN: 0016-5085.
  • Saperas, E.; Fernandez, Pl., (1995), "A man of 83 with generalized bone pains and a biological malabsorption syndrome", Medicina clínica, vol. 104, pp. 387-395, ISSN: 0025-7753.
Capítulos de libro
  • Saperas, E., (2016), "Hemorragia Gastrointestinal", Medicina Interna. Farreras/Rozman, pp. 223-230, Elsevier España S.L..
  • Saperas, E., (26/06/2012), "Hemorragia Gastrointestinal. Enfermedades del aparato digestivo", Medicina Interna, Elsevier España S.L.. ISBN: 9788480868969.
  • Feu, F.; Saperas, E., (01/01/2012), "Hemorragia Digestiva Baja", Tratamiento de las enfermedades Gastroenterológicas, pp. 361-369, J.Ponce. ISBN: 978-84-7592-722-0.

Actividades

  • Reunión Anual Asociación Española de Gastroenterología Ponència "Colonoscopia de luz blanca de alta definición vs cromoendoscopia para la vigilancia del síndrome de Lynch. Estudio multicéntrico, aleatorizado, controlado y paralelo (Estudio Endolynch)", 2019.
  • Reunión Anual Asociación Española de Gastroenterología Presentació de comunicació "La estrategia de "diagnose and disregard" se puede implementar en pacientes con síndrome de Lynch cuando el diagnóstico óptico es realizado por colonoscopistas expertos", 2019.
  • Congrés de la Societat Catalana de Digestologia Presentació de comunicació "Colonoscopia de luz blanca de alta definición vs cromoendoscopia para la vigilancia del Síndrome de Lynch. Estudio multicéntrico, aleatorizado, controlado y parelelo (Estudio Endolynch)", 2019.
  • Digestive Disease Week Ponència "Cost-Effectiveness of Prophylactic Clipping After Colorectal Endoscopic Mucosal Resection and Economic Impact According to a Bleeding Risk Score", 2016.
  • Digestive Disease Week Ponència "Incidence of Colonic Neoplasia in Patients With Serrated Polyposis Syndrome Who Undergo Endoscopic Surveillance: A Multicenter Study", 2016.
  • Digestive Disease Week Ponència "Delayed Bleeding Risk Score for Colorectal Endoscopic Mucosal Resection.", 2015.
  • Digestive Disease Week Presentació de comunicació "Delayed bleeding after endoscopic mucosal resection of large colorectal lesions. A prospective multicenter Spanish study.", 2014.