Dr Rosalía Rodríguez, director of the Bachelor’s Degree in Biomedical Sciences and member of the NeuroLipid Group, has recently published a review titled “
An overview of nanomedicines for neuron Targeting”, in the journal
Nanomedicine, which analyses the most relevant advances in nanomedicine design. The article also offers a review of strategies for administering neuronal pharmaceuticals that could potentially bridge the gap between laboratory and bedside treatment in neurology.
“Although the literature we have reviewed so far focuses on targeting the brain with nanomedicines in general, none of the studies are concerned explicitly with neurons. This review highlighted some interesting tests that could successfully bridge the gap between laboratory studies and patient studies” explained Dr Rosalía Rodríguez.
This revision was conducted as part of the CONCORD project, undertaken bilaterally between UIC Barcelona and the Innovation Centre of NanoMedicine in Kawasaki (Japan). The study, led by Dr Rosalía Rodríguez and Dr Sabina Quader, aimed to develop polymeric nanomedicines containing drugs that inhibit the CPT1 protein, which is key to lipid metabolism in neurons. “Underlying neuron-related disorders have an enormous impact on our society”, revealed Rodriguez, “including a great number of conditions with neuronal changes such as neurodegenerative diseases and metabolic disorders”. This article also led to an interview with the two researchers published on
Neuro Central, an online resource from the publishers Future Science Group that reports on the most innovative developments in neurology and neuroscience.
Similarly, as part of this research, Jesús García-Chica, a PhD student also collaborating on the CONCORD project, gave a spoken presentation titled “Development of C75-CoA-loaded polymeric nanomedicines to inhibit CPT1 in specific brain cells” at the international NanoBioMed conference, held online last July.
In January 2019, the CONCORD project received funding from the Ministry of Science, Innovation and Universities to help young researchers in the field of nanomedicine to carry out their research.
