Postdoctoral Researcher: Catalan Institute of Nanoscience and Nanotechnology, ICN2, Spain Jul 2017 – Jan 2020. NanoBiosensors and Bioanalytical Applications Group.
Design and development of compact and miniaturized optical setups for SPR and LSPR biosensing using angular and spectral interrogation, enabling multiplexed measurements of bioanalytes (micro-RNA, proteins, etc)
• Simulation and fabrication of plasmonic nanostructures for DNA hybridization and Antibody based biosensing schemes.
• Large area and low-cost nanofabrication of plasmonic nanostructures (optical nanogap antennas, nanoholes, nanogratings) using colloidal lithography, nanoimprinting (NIL) and Soft-lithography methodologies to.
• Design and fabrication of microfluidic chips using standard PDMS microfluidic technique. Low cost microfluidic fabrication using mask-less photolithography and inkjet printing processes. Design of active microfluidics valves and peristaltic pumps enabling miniaturization of optofluidic systems.
• Microespectroscopy setup for characterization of plasmonic nanostructures. Electronic instrumentation for signal acquisition.
• Design and evaluation of a sensing system combining capillary gel electrophoresis with SPR (CGE-SPR) and LSPR techniques for direct and real time detection of molecular compounds.
• Design of capillary microfluidics in microchannels for multiplex detection of bioanalytes.
Postdoctoral Researcher: Tokyo Institute of Technology, Japan. Dept. Chemical Sciences and Engineering. Jun 2015 – Apr 2017
• Development of biophotonic applications based on plasmonic and non-plasmonic nanostructures for analysis of biomolecular spectroscopy and cell biological analytes.
• Surface Enhances Raman spectroscopy (SERS) for monitoring the dynamic of the cell’s ligand-receptor. Imaging of cell’s focal adhesion using plasmonic nanoantennas.
• Micro and Nanofabrication process of plasmonic structures and microfluidic chips for integrated solutions.
• Design for of biosensor platform for Point-of-Care testing (POCT) systems for detection of biomarkers and exosomes based on electrophoretic and photonics principles. PhD Bioengineering. The University of Tokyo, Japan 2011-2014 Bioengineering Department.
• Conducted research into the development of biosensing methods for single cell studies using Surface Plasmon Resonance (SPR) for biological applications.
• Numerical simulation of optical response of plasmonic nanostructures.
• Modern Nano-Microfabrication techniques for the design of biological sensors. Electron Beam Lithography (EBL), Etching, Focused Ion Beam (FIB), Pulsed Laser Deposition (PLD), Chemical and Physical Vapor Deposition, etc.
• Various metallic oxides nanowires and film fabrication SnO2, ZnO2.
• Characterization techniques: Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), Atomic Force Microscopy (AFM), Optical Spectroscopy, Terahertz, UV- Visible spectrometry, X-Ray Diffraction (XRD).
• Surface biofunctionalization. Cell manipulation. Immunostaining confocal microscopy.
• Design of Optical System for spectroscopy using LSPR and Raman Spectroscopy.
• Design and Fabrication of Microfluidic chips using PDMS. 3D printer prototype design and fabrication. Laser cutting and ablation for prototyping.
Master Science (Digital Systems, Biomedical Engineering) 2003-2005 Higher Polytechnic Institute (ISPJAE), Havana, Cuba.
• Design of digital architectures for embedded systems based on microcontrollers.
• Principles of Biosensors. Digital Signal Processing and Object-Oriented Programming.
• Bioinstrumentation. Specialized tools for design of biomedical equipment.
Bachelor of Electronic and Telecommunications Engineering 1994-1999
Higher Polytechnic Institute (ISPJAE), Havana, Cuba. Applied Physics and Chemistry subjects related to electronic discipline. Analog and digital electronic principles and circuitry design. Fundamentals of telecommunications and digital network systems. Basics of biomedical devices and systems.