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ALDEA MALO, Martí

ALDEA MALO, Martí

Professor Catedràtic
DEPARTMENT OF BASIC SCIENCIES
Department of Basic Areas

Contact

maldea@uic.es
ORCID
  • Academic training
  • Professional experience
  • Projects
    • Competitive
  • Publications
    • Articles
  • Subjects taught
  • Otros
  • Universitat Autònoma de Barcelona

1982 - Doctor in Biological Science, UNIVERSITAT AUTÒNOMA DE BARCELONA
1978 - Bachelor's Degree in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA
1977 - Bachelor's Degree in Biological Sciences, UNIVERSITAT AUTÒNOMA DE BARCELONA
2010 Research Professor, Higher Council for Scientific Research
2003-2009 University Professor, Universitat de Lleida
1992-2002 Full University Professor, Universitat de Lleida
1988-1991 Postdoctoral Reincorporation Fellow, C. Biological Research. CSIC
1987-1988 Research Associate, Dept. of Genetics. UGA. USES.
1985-1986 Postdoctoral Fellow, Dept. of Genetics. UGA. USES.
1983-1985 Postdoctoral Fellow, Cell Biology Institute. CSIC
1978-1981 Doctoral Scholar, Dept. Microbiology. UAB.
1977-1983 Assistant Professor, C. General Biology. UAB.
  • Ultradynamic protein assemblies and network channeling
    PI: Aldea, M. Start date: 01/01/2024 End date: 31/12/2026
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2022-141460NB-I00
  • Protein cluster dynamics and network channeling
    PI: Aldea, M. Start date: 01/06/2020 End date: 31/05/2023
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2019-109638GB-I00
  • Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging
    PI: Aldea, M. Start date: 30/12/2016 End date: 29/12/2019
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad Financing entity code: BFU2016-80234-R
  • Prions and aggregons as inhibitors of Start: a path to cell ageing.
    PI: Aldea, M. Start date: 01/01/2014 End date: 31/12/2016
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad
  • Molecular cell, Transcriptomic balance and optimal growth are determined by cell size
    Name: Vidal, P.; Pérez, A.; Yahya, G.; Aldea, M. Role: Autor Publishing date: 2024
    Start page: 3288 End page: 3301 Vol.: 84 No.: 17
    DOI: https://dx.doi.org/10.1016/j.molcel.2024.07.005 ISSN or title: 1097-2765
  • Science advances, Mad3 modulates the G1 Cdk and acts as a timer in the Start network
    Name: Pérez-Paredes, A.; Artés, M.H.; Moreno, D.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2022
    Vol.: 8 No.: 18
    DOI: https://dx.doi.org/10.1126/sciadv.abm4086 ISSN or title: 2375-2548
  • Journal of cell biology, Stress granules display bistable dynamics modulated by Cdk
    Name: Yahya, G.; Pérez-Paredes, A.; Mendoza, M.; Parisi, E.; Moreno, D.; Artés, M.H.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2021
    Vol.: 220 No.: 3
    DOI: https://dx.doi.org/10.1083/jcb.202005102 ISSN or title: 0021-9525
  • eLife, Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1
    Name: Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 8
    DOI: https://dx.doi.org/10.7554/eLife.48240 ISSN or title: 2050-084X
  • Methods in Molecular Biology, Coincidence analysis of molecular dynamics by raster image correlation spectroscopy
    Name: Moreno, D.; Aldea, M. Role: Autor Publishing date: 2019
    Start page: 375 End page: 384 Vol.: 2040
    DOI: https://dx.doi.org/10.1007/978-1-4939-9686-5_17 ISSN or title: 1940-6029 10643745
  • Life Science Alliance, Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress
    Name: Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 2 No.: 2
    DOI: https://dx.doi.org/10.26508/lsa.201800277 ISSN or title: 2575-1077
  • Embo journal, Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression
    Name: Parisi, E.; Yahya, G.; Flores, A.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 37 No.: 16
    DOI: https://dx.doi.org/10.15252/embj.201798724 ISSN or title: 0261-4189
  • PLOS biology, Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
    Name: Martínez-Láinez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 16 No.: 8
    DOI: https://dx.doi.org/10.1371/journal.pbio.2005388 ISSN or title: 1544-9173
  • Frontiers in cell and developmental biology, Growth Rate as a Direct Regulator of the Start Network to Set Cell Size
    Name: Aldea, M.; Jenkins, K.; Csikász, A. Role: Autor Publishing date: 2017
    Start page: 57 End page: 62 Vol.: 5
    DOI: https://dx.doi.org/10.3389/fcell.2017.00057 ISSN or title: 2296-634X
  • Current biology, Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell
    Name: Aldea, M. Role: Autor Publishing date: 2017
    Start page: 773 End page: 783 Vol.: 27
    ISSN or title: 0960-9822
  • Scientific Reports, Nucleosome architecture throughout the cell cycle
    Name: Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M. Role: Autor Publishing date: 2016
    Start page: 1 End page: 11 Vol.: 6 No.: 19729
    DOI: https://dx.doi.org/10.1038/srep19729 ISSN or title: 2045-2322
  • Nature methods, Inntags: small self-structured epitopes for innocuous protein tagging
    Name: Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M. Role: Autor Publishing date: 2015
    Start page: 955 End page: 958 Vol.: 12 No.: 10
    DOI: https://dx.doi.org/10.1038/nmeth.3556 ISSN or title: 1548-7091
  • Molecular cell, A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.
    Name: Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2014
    Start page: 115 End page: 126 Vol.: 53
    DOI: https://dx.doi.org/10.1016/j.molcel.2013.11.015 ISSN or title: 1097-2765
  • Mol Cell Biol., Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry
    Name: Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J. Role: Autor Publishing date: 2013
    Start page: 1273 End page: 1284 Vol.: 33(7)
    ISSN or title: 1098-5549
  • Nature communications, The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
    Name: Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2012
    Start page: 1 End page: 11 Vol.: 3 No.: 1012
    DOI: https://dx.doi.org/10.1038/ncomms2015 ISSN or title: 2041-1723
  • Genome biology, The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
    Name: Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M. Role: Autor Publishing date: 2010
    Start page: 1 End page: 9 Vol.: 11 No.: 6
    DOI: https://dx.doi.org/10.1186/gb-2010-11-6-r67 ISSN or title: 1474-760X
  • Molecular cell, Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry
    Name: Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2007
    Start page: 649 End page: 662 Vol.: 26 No.: 5
    ISSN or title: 1097-2765
  • Embo journal, Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.
    Name: Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F. Role: Autor Publishing date: 2006
    Start page: 2338 End page: 2346 Vol.: 25
    ISSN or title: 0261-4189
  • Molecular and cellular biology, The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.
    Name: Clotet, J.; Garí, E.; Aldea, M.; Ariño, J. Role: Autor Publishing date: 1999
    Start page: 2408 End page: 2415 Vol.: 19
    ISSN or title: 0270-7306
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology

Academic training

  • Otros
  • Universitat Autònoma de Barcelona

1982 - Doctor in Biological Science, UNIVERSITAT AUTÒNOMA DE BARCELONA
1978 - Bachelor's Degree in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA
1977 - Bachelor's Degree in Biological Sciences, UNIVERSITAT AUTÒNOMA DE BARCELONA

Professional experience

2010 Research Professor, Higher Council for Scientific Research
2003-2009 University Professor, Universitat de Lleida
1992-2002 Full University Professor, Universitat de Lleida
1988-1991 Postdoctoral Reincorporation Fellow, C. Biological Research. CSIC
1987-1988 Research Associate, Dept. of Genetics. UGA. USES.
1985-1986 Postdoctoral Fellow, Dept. of Genetics. UGA. USES.
1983-1985 Postdoctoral Fellow, Cell Biology Institute. CSIC
1978-1981 Doctoral Scholar, Dept. Microbiology. UAB.
1977-1983 Assistant Professor, C. General Biology. UAB.

Projects

Competitive

  • Ultradynamic protein assemblies and network channeling
    PI: Aldea, M. Start date: 01/01/2024 End date: 31/12/2026
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2022-141460NB-I00
  • Protein cluster dynamics and network channeling
    PI: Aldea, M. Start date: 01/06/2020 End date: 31/05/2023
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2019-109638GB-I00
  • Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging
    PI: Aldea, M. Start date: 30/12/2016 End date: 29/12/2019
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad Financing entity code: BFU2016-80234-R
  • Prions and aggregons as inhibitors of Start: a path to cell ageing.
    PI: Aldea, M. Start date: 01/01/2014 End date: 31/12/2016
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad

Publications

Articles

  • Molecular cell, Transcriptomic balance and optimal growth are determined by cell size
    Name: Vidal, P.; Pérez, A.; Yahya, G.; Aldea, M. Role: Autor Publishing date: 2024
    Start page: 3288 End page: 3301 Vol.: 84 No.: 17
    DOI: https://dx.doi.org/10.1016/j.molcel.2024.07.005 ISSN or title: 1097-2765
  • Science advances, Mad3 modulates the G1 Cdk and acts as a timer in the Start network
    Name: Pérez-Paredes, A.; Artés, M.H.; Moreno, D.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2022
    Vol.: 8 No.: 18
    DOI: https://dx.doi.org/10.1126/sciadv.abm4086 ISSN or title: 2375-2548
  • Journal of cell biology, Stress granules display bistable dynamics modulated by Cdk
    Name: Yahya, G.; Pérez-Paredes, A.; Mendoza, M.; Parisi, E.; Moreno, D.; Artés, M.H.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2021
    Vol.: 220 No.: 3
    DOI: https://dx.doi.org/10.1083/jcb.202005102 ISSN or title: 0021-9525
  • eLife, Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1
    Name: Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 8
    DOI: https://dx.doi.org/10.7554/eLife.48240 ISSN or title: 2050-084X
  • Methods in Molecular Biology, Coincidence analysis of molecular dynamics by raster image correlation spectroscopy
    Name: Moreno, D.; Aldea, M. Role: Autor Publishing date: 2019
    Start page: 375 End page: 384 Vol.: 2040
    DOI: https://dx.doi.org/10.1007/978-1-4939-9686-5_17 ISSN or title: 1940-6029 10643745
  • Life Science Alliance, Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress
    Name: Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 2 No.: 2
    DOI: https://dx.doi.org/10.26508/lsa.201800277 ISSN or title: 2575-1077
  • Embo journal, Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression
    Name: Parisi, E.; Yahya, G.; Flores, A.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 37 No.: 16
    DOI: https://dx.doi.org/10.15252/embj.201798724 ISSN or title: 0261-4189
  • PLOS biology, Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
    Name: Martínez-Láinez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 16 No.: 8
    DOI: https://dx.doi.org/10.1371/journal.pbio.2005388 ISSN or title: 1544-9173
  • Frontiers in cell and developmental biology, Growth Rate as a Direct Regulator of the Start Network to Set Cell Size
    Name: Aldea, M.; Jenkins, K.; Csikász, A. Role: Autor Publishing date: 2017
    Start page: 57 End page: 62 Vol.: 5
    DOI: https://dx.doi.org/10.3389/fcell.2017.00057 ISSN or title: 2296-634X
  • Current biology, Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell
    Name: Aldea, M. Role: Autor Publishing date: 2017
    Start page: 773 End page: 783 Vol.: 27
    ISSN or title: 0960-9822
  • Scientific Reports, Nucleosome architecture throughout the cell cycle
    Name: Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M. Role: Autor Publishing date: 2016
    Start page: 1 End page: 11 Vol.: 6 No.: 19729
    DOI: https://dx.doi.org/10.1038/srep19729 ISSN or title: 2045-2322
  • Nature methods, Inntags: small self-structured epitopes for innocuous protein tagging
    Name: Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M. Role: Autor Publishing date: 2015
    Start page: 955 End page: 958 Vol.: 12 No.: 10
    DOI: https://dx.doi.org/10.1038/nmeth.3556 ISSN or title: 1548-7091
  • Molecular cell, A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.
    Name: Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2014
    Start page: 115 End page: 126 Vol.: 53
    DOI: https://dx.doi.org/10.1016/j.molcel.2013.11.015 ISSN or title: 1097-2765
  • Mol Cell Biol., Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry
    Name: Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J. Role: Autor Publishing date: 2013
    Start page: 1273 End page: 1284 Vol.: 33(7)
    ISSN or title: 1098-5549
  • Nature communications, The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
    Name: Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2012
    Start page: 1 End page: 11 Vol.: 3 No.: 1012
    DOI: https://dx.doi.org/10.1038/ncomms2015 ISSN or title: 2041-1723
  • Genome biology, The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
    Name: Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M. Role: Autor Publishing date: 2010
    Start page: 1 End page: 9 Vol.: 11 No.: 6
    DOI: https://dx.doi.org/10.1186/gb-2010-11-6-r67 ISSN or title: 1474-760X
  • Molecular cell, Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry
    Name: Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2007
    Start page: 649 End page: 662 Vol.: 26 No.: 5
    ISSN or title: 1097-2765
  • Embo journal, Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.
    Name: Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F. Role: Autor Publishing date: 2006
    Start page: 2338 End page: 2346 Vol.: 25
    ISSN or title: 0261-4189
  • Molecular and cellular biology, The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.
    Name: Clotet, J.; Garí, E.; Aldea, M.; Ariño, J. Role: Autor Publishing date: 1999
    Start page: 2408 End page: 2415 Vol.: 19
    ISSN or title: 0270-7306
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology