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ALDEA MALO, Martí

ALDEA MALO, Martí

Professor Catedràtic
DEPARTMENT OF BASIC SCIENCIES
Department of Basic Areas

Contact

maldea@uic.es
ORCID
  • Academic training
  • Professional experience
  • Projects
    • Competitive
  • Publications
    • Articles
  • Subjects taught
  • Otros
  • Universitat Autònoma de Barcelona

Doctor in Biological Science, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biological Sciences, UNIVERSITAT AUTÒNOMA DE BARCELONA
2010 Research Professor, Higher Council for Scientific Research
2003-2009 University Professor, Universitat de Lleida
1992-2002 Full University Professor, Universitat de Lleida
1988-1991 Postdoctoral Reincorporation Fellow, C. Biological Research. CSIC
1987-1988 Research Associate, Dept. of Genetics. UGA. USES.
1985-1986 Postdoctoral Fellow, Dept. of Genetics. UGA. USES.
1983-1985 Postdoctoral Fellow, Cell Biology Institute. CSIC
1978-1981 Doctoral Scholar, Dept. Microbiology. UAB.
1977-1983 Assistant Professor, C. General Biology. UAB.
  • Ultradynamic protein assemblies and network channeling
    PI: Aldea, M. Start date: 01/01/2024 End date: 31/12/2026
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2022-141460NB-I00
  • Protein cluster dynamics and network channeling
    PI: Aldea, M. Start date: 01/06/2020 End date: 31/05/2023
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2019-109638GB-I00
  • Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging
    PI: Aldea, M. Start date: 30/12/2016 End date: 29/12/2019
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad Financing entity code: BFU2016-80234-R
  • Prions and aggregons as inhibitors of Start: a path to cell ageing.
    PI: Aldea, M. Start date: 01/01/2014 End date: 31/12/2016
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad
  • Molecular cell, Transcriptomic balance and optimal growth are determined by cell size
    Name: Vidal, P.; Pérez, A.; Yahya, G.; Aldea, M. Role: Autor Publishing date: 2024
    Start page: 3288 End page: 3301 Vol.: 84 No.: 17
    DOI: https://dx.doi.org/10.1016/j.molcel.2024.07.005 ISSN or title: 1097-2765
  • Science advances, Mad3 modulates the G1 Cdk and acts as a timer in the Start network
    Name: Pérez-Paredes, A.; Artés, M.H.; Moreno, D.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2022
    Vol.: 8 No.: 18
    DOI: https://dx.doi.org/10.1126/sciadv.abm4086 ISSN or title: 2375-2548
  • Journal of cell biology, Stress granules display bistable dynamics modulated by Cdk
    Name: Yahya, G.; Pérez-Paredes, A.; Mendoza, M.; Parisi, E.; Moreno, D.; Artés, M.H.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2021
    Vol.: 220 No.: 3
    DOI: https://dx.doi.org/10.1083/jcb.202005102 ISSN or title: 0021-9525
  • eLife, Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1
    Name: Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 8
    DOI: https://dx.doi.org/10.7554/eLife.48240 ISSN or title: 2050-084X
  • Methods in Molecular Biology, Coincidence analysis of molecular dynamics by raster image correlation spectroscopy
    Name: Moreno, D.; Aldea, M. Role: Autor Publishing date: 2019
    Start page: 375 End page: 384 Vol.: 2040
    DOI: https://dx.doi.org/10.1007/978-1-4939-9686-5_17 ISSN or title: 1940-6029 10643745
  • Life Science Alliance, Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress
    Name: Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 2 No.: 2
    DOI: https://dx.doi.org/10.26508/lsa.201800277 ISSN or title: 2575-1077
  • Embo journal, Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression
    Name: Parisi, E.; Yahya, G.; Flores, A.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 37 No.: 16
    DOI: https://dx.doi.org/10.15252/embj.201798724 ISSN or title: 0261-4189
  • PLOS biology, Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
    Name: Martínez-Láinez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 16 No.: 8
    DOI: https://dx.doi.org/10.1371/journal.pbio.2005388 ISSN or title: 1544-9173
  • Frontiers in cell and developmental biology, Growth Rate as a Direct Regulator of the Start Network to Set Cell Size
    Name: Aldea, M.; Jenkins, K.; Csikász, A. Role: Autor Publishing date: 2017
    Start page: 57 End page: 62 Vol.: 5
    DOI: https://dx.doi.org/10.3389/fcell.2017.00057 ISSN or title: 2296-634X
  • Current biology, Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell
    Name: Aldea, M. Role: Autor Publishing date: 2017
    Start page: 773 End page: 783 Vol.: 27
    ISSN or title: 0960-9822
  • Scientific Reports, Nucleosome architecture throughout the cell cycle
    Name: Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M. Role: Autor Publishing date: 2016
    Start page: 1 End page: 11 Vol.: 6 No.: 19729
    DOI: https://dx.doi.org/10.1038/srep19729 ISSN or title: 2045-2322
  • Nature methods, Inntags: small self-structured epitopes for innocuous protein tagging
    Name: Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M. Role: Autor Publishing date: 2015
    Start page: 955 End page: 958 Vol.: 12 No.: 10
    DOI: https://dx.doi.org/10.1038/nmeth.3556 ISSN or title: 1548-7091
  • Molecular cell, A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.
    Name: Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2014
    Start page: 115 End page: 126 Vol.: 53
    DOI: https://dx.doi.org/10.1016/j.molcel.2013.11.015 ISSN or title: 1097-2765
  • Mol Cell Biol., Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry
    Name: Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J. Role: Autor Publishing date: 2013
    Start page: 1273 End page: 1284 Vol.: 33(7)
    ISSN or title: 1098-5549
  • Nature communications, The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
    Name: Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2012
    Start page: 1 End page: 11 Vol.: 3 No.: 1012
    DOI: https://dx.doi.org/10.1038/ncomms2015 ISSN or title: 2041-1723
  • Genome biology, The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
    Name: Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M. Role: Autor Publishing date: 2010
    Start page: 1 End page: 9 Vol.: 11 No.: 6
    DOI: https://dx.doi.org/10.1186/gb-2010-11-6-r67 ISSN or title: 1474-760X
  • Molecular cell, Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry
    Name: Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2007
    Start page: 649 End page: 662 Vol.: 26 No.: 5
    ISSN or title: 1097-2765
  • Embo journal, Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.
    Name: Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F. Role: Autor Publishing date: 2006
    Start page: 2338 End page: 2346 Vol.: 25
    ISSN or title: 0261-4189
  • Molecular and cellular biology, The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.
    Name: Clotet, J.; Garí, E.; Aldea, M.; Ariño, J. Role: Autor Publishing date: 1999
    Start page: 2408 End page: 2415 Vol.: 19
    ISSN or title: 0270-7306
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology

Academic training

  • Otros
  • Universitat Autònoma de Barcelona

Doctor in Biological Science, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biochemistry, UNIVERSITAT AUTÒNOMA DE BARCELONA
Bachelor's Degree in Biological Sciences, UNIVERSITAT AUTÒNOMA DE BARCELONA

Professional experience

2010 Research Professor, Higher Council for Scientific Research
2003-2009 University Professor, Universitat de Lleida
1992-2002 Full University Professor, Universitat de Lleida
1988-1991 Postdoctoral Reincorporation Fellow, C. Biological Research. CSIC
1987-1988 Research Associate, Dept. of Genetics. UGA. USES.
1985-1986 Postdoctoral Fellow, Dept. of Genetics. UGA. USES.
1983-1985 Postdoctoral Fellow, Cell Biology Institute. CSIC
1978-1981 Doctoral Scholar, Dept. Microbiology. UAB.
1977-1983 Assistant Professor, C. General Biology. UAB.

Projects

Competitive

  • Ultradynamic protein assemblies and network channeling
    PI: Aldea, M. Start date: 01/01/2024 End date: 31/12/2026
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2022-141460NB-I00
  • Protein cluster dynamics and network channeling
    PI: Aldea, M. Start date: 01/06/2020 End date: 31/05/2023
    Financing entity: Agencia EStatal de Investigación Financing entity code: PID2019-109638GB-I00
  • Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging
    PI: Aldea, M. Start date: 30/12/2016 End date: 29/12/2019
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad Financing entity code: BFU2016-80234-R
  • Prions and aggregons as inhibitors of Start: a path to cell ageing.
    PI: Aldea, M. Start date: 01/01/2014 End date: 31/12/2016
    Financing entity: MINE - MINECO. Ministerio de Economía y Competitividad

Publications

Articles

  • Molecular cell, Transcriptomic balance and optimal growth are determined by cell size
    Name: Vidal, P.; Pérez, A.; Yahya, G.; Aldea, M. Role: Autor Publishing date: 2024
    Start page: 3288 End page: 3301 Vol.: 84 No.: 17
    DOI: https://dx.doi.org/10.1016/j.molcel.2024.07.005 ISSN or title: 1097-2765
  • Science advances, Mad3 modulates the G1 Cdk and acts as a timer in the Start network
    Name: Pérez-Paredes, A.; Artés, M.H.; Moreno, D.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2022
    Vol.: 8 No.: 18
    DOI: https://dx.doi.org/10.1126/sciadv.abm4086 ISSN or title: 2375-2548
  • Journal of cell biology, Stress granules display bistable dynamics modulated by Cdk
    Name: Yahya, G.; Pérez-Paredes, A.; Mendoza, M.; Parisi, E.; Moreno, D.; Artés, M.H.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2021
    Vol.: 220 No.: 3
    DOI: https://dx.doi.org/10.1083/jcb.202005102 ISSN or title: 0021-9525
  • eLife, Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1
    Name: Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 8
    DOI: https://dx.doi.org/10.7554/eLife.48240 ISSN or title: 2050-084X
  • Methods in Molecular Biology, Coincidence analysis of molecular dynamics by raster image correlation spectroscopy
    Name: Moreno, D.; Aldea, M. Role: Autor Publishing date: 2019
    Start page: 375 End page: 384 Vol.: 2040
    DOI: https://dx.doi.org/10.1007/978-1-4939-9686-5_17 ISSN or title: 1940-6029 10643745
  • Life Science Alliance, Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress
    Name: Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M. Role: Autor Publishing date: 2019
    Vol.: 2 No.: 2
    DOI: https://dx.doi.org/10.26508/lsa.201800277 ISSN or title: 2575-1077
  • Embo journal, Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression
    Name: Parisi, E.; Yahya, G.; Flores, A.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 37 No.: 16
    DOI: https://dx.doi.org/10.15252/embj.201798724 ISSN or title: 0261-4189
  • PLOS biology, Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast
    Name: Martínez-Láinez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M. Role: Autor Publishing date: 2018
    Vol.: 16 No.: 8
    DOI: https://dx.doi.org/10.1371/journal.pbio.2005388 ISSN or title: 1544-9173
  • Frontiers in cell and developmental biology, Growth Rate as a Direct Regulator of the Start Network to Set Cell Size
    Name: Aldea, M.; Jenkins, K.; Csikász, A. Role: Autor Publishing date: 2017
    Start page: 57 End page: 62 Vol.: 5
    DOI: https://dx.doi.org/10.3389/fcell.2017.00057 ISSN or title: 2296-634X
  • Current biology, Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell
    Name: Aldea, M. Role: Autor Publishing date: 2017
    Start page: 773 End page: 783 Vol.: 27
    ISSN or title: 0960-9822
  • Scientific Reports, Nucleosome architecture throughout the cell cycle
    Name: Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M. Role: Autor Publishing date: 2016
    Start page: 1 End page: 11 Vol.: 6 No.: 19729
    DOI: https://dx.doi.org/10.1038/srep19729 ISSN or title: 2045-2322
  • Nature methods, Inntags: small self-structured epitopes for innocuous protein tagging
    Name: Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M. Role: Autor Publishing date: 2015
    Start page: 955 End page: 958 Vol.: 12 No.: 10
    DOI: https://dx.doi.org/10.1038/nmeth.3556 ISSN or title: 1548-7091
  • Molecular cell, A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.
    Name: Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2014
    Start page: 115 End page: 126 Vol.: 53
    DOI: https://dx.doi.org/10.1016/j.molcel.2013.11.015 ISSN or title: 1097-2765
  • Mol Cell Biol., Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry
    Name: Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J. Role: Autor Publishing date: 2013
    Start page: 1273 End page: 1284 Vol.: 33(7)
    ISSN or title: 1098-5549
  • Nature communications, The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation
    Name: Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M. Role: Autor Publishing date: 2012
    Start page: 1 End page: 11 Vol.: 3 No.: 1012
    DOI: https://dx.doi.org/10.1038/ncomms2015 ISSN or title: 2041-1723
  • Genome biology, The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle
    Name: Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M. Role: Autor Publishing date: 2010
    Start page: 1 End page: 9 Vol.: 11 No.: 6
    DOI: https://dx.doi.org/10.1186/gb-2010-11-6-r67 ISSN or title: 1474-760X
  • Molecular cell, Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry
    Name: Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M. Role: Autor Publishing date: 2007
    Start page: 649 End page: 662 Vol.: 26 No.: 5
    ISSN or title: 1097-2765
  • Embo journal, Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.
    Name: Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F. Role: Autor Publishing date: 2006
    Start page: 2338 End page: 2346 Vol.: 25
    ISSN or title: 0261-4189
  • Molecular and cellular biology, The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.
    Name: Clotet, J.; Garí, E.; Aldea, M.; Ariño, J. Role: Autor Publishing date: 1999
    Start page: 2408 End page: 2415 Vol.: 19
    ISSN or title: 0270-7306
Course 2024-2025 - Period: 01/09/2024 - 31/08/2025
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2023-2024 - Period: 01/09/2023 - 31/08/2024
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2022-2023 - Period: 01/09/2022 - 31/08/2023
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2021-2022 - Period: 01/09/2021 - 31/08/2022
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2020-2021 - Period: 01/09/2020 - 31/08/2021
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2019-2020 - Period: 01/09/2019 - 31/08/2020
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2018-2019 - Period: 01/09/2018 - 31/08/2019
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2017-2018 - Period: 01/09/2017 - 31/08/2018
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2016-2017 - Period: 01/09/2016 - 31/08/2017
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2015-2016 - Period: 01/09/2015 - 31/08/2016
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Molecular Biology
    • - Cell Biology
Course 2014-2015 - Period: 01/09/2014 - 31/08/2015
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology
    • - Molecular Biology
Course 2013-2014 - Period: 01/09/2013 - 31/08/2014
  • Bachelor’s Degree
    Bachelor's Degree in Medicine
    • - Cell Biology