15/06/2017

The first quartile journal 'Molecular Nutrition & Food Research' publishes a paper led by researchers Núria Casals and Rosalía Rodríguez from the Department of Basic Sciences

The research, led by the Department of Basic Sciences of the Faculty of Medicine and Health Sciences, was undertaken as part of the project headed by Dr Rosa Lamuela at the UB, in cooperation with researchers from the UAB and the University of Seville. Using the benefits of the Mediterranean diet as a starting point, the paper focuses on the positive effects of sofrito, a sauce made by sautéing tomatoes, garlic and onion in olive oil and a key ingredient in many Mediterranean recipes, on obesity.

Under the title “Mediterranean tomato-based sofrito protects against vascular alterations in obese Zucker rats by preserving NO bioavailability”, the research emphasises the nutritional value of sofrito and explores its potentially beneficial effects on obesity-related vascular and metabolic alterations in an animal model of this pathology. The main reason is the high content of bioactive compounds (polyphenols and carotenoids) in tomatoes and olive oil and the sofrito’s lipid matrix, which preserves the integrity of its bioactive components.

After studying and monitoring the effects of incorporating sofrito into the diet of both lean and obese rats, the team of researchers concluded that tomato-based sofrito provides protection against vascular alternations that may precede major obesity-associated cardiometabolic complications. In doing so, the findings also substantiate and help explain the Mediterranean diet’s therapeutic properties for the treatment of highly prevalent diseases such as obesity and diabetes.