03/06/2021

Researchers from the Faculty of Dentistry and the Bioengineering Institute of Technology demonstrate the antibacterial role nanoparticles play in endodontics

The group of researchers has developed new antibacterial nanoparticles capable of achieving greater penetration into dentinal tubules than the methods currently used in endodontics

This use of nanotechnology in the field of medicine is taking a leading role in new therapies. However, its use in dentistry is still in its very early stages, especially in the field of endodontics. Therefore, the team formed by Fernando Durán-Sindreu, José A. González and Firas Elmsmari from the Department of Endodontics at the Faculty of Dentistry; Román Pérez from the Bioengineering Institute of Technology, and Elena Sánchez and María L. Garcia from the Department of Pharmacy and Pharmaceutical Technology and Physicochemistry in the Faculty of Pharmacy and Food Sciences at the University of Barcelona, carried out the study Composition comprising nanoparticles, method for the preparation of a composition comprising nanoparticles and uses of the composition for dental treatment. 

Through their research, the group developed and optimised the formulation of nanoparticles using various physicochemical techniques, to be used as intra-endodontic antibacterial agents. “Our development has been the first to apply nanotechnology to bacterial disinfection in endodontics by encapsulating an active ingredient through the development of a specific formulation”, say the authors of the study. 

This project was financed using FEDER Otris funds and managed by the AGAUR. It is the result of one of six patent applications submitted by UIC Barcelona in 2020. 
 

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