Soledad Perez Amodio studied Biochemistry at the University of the Republic of Uruguay (UDELAR). After completing her degree, she moved to London, to the Department of Clinical Biochemistry, Bart's Hospital, Queen Mary University with a grant from the ALFA program (Latin AMERICA-university training). Two years later she began a PhD in Cellular and Molecular Biology at the department of Oral Cell Biology, University of Amsterdam.
After completing her doctorate, she worked as a postdoctoral fellow at the Department of Cell Biology, Free University of Amsterdam. She then joined the Tissue Regeneration group at the University of Tweente, Enchede (2005-2007). In 2007, she joined the department of Plastic and Reconstructive Surgery, Erasmus Medical Center, Rotterdam. In 2012, she began as a Senior Researcher at the Bioengineering Institute of Catalonia.
Her research is based on the design of bioactive biomaterials for tissue regeneration.